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Targeting autophagy, oxidative stress, and ER stress for neurodegenerative disease treatment
Protein homeostasis is a vital process for cell function and, therefore, disruption of the
molecular mechanisms involved in this process, such as autophagy, may contribute to …
molecular mechanisms involved in this process, such as autophagy, may contribute to …
Artificial intelligence in early drug discovery enabling precision medicine
Introduction: Precision medicine is the concept of treating diseases based on environmental
factors, lifestyles, and molecular profiles of patients. This approach has been found to …
factors, lifestyles, and molecular profiles of patients. This approach has been found to …
[HTML][HTML] Envisioning the future of personalized medicine: Role and realities of digital twins
A Vallée - Journal of Medical Internet Research, 2024 - jmir.org
Digital twins have emerged as a groundbreaking concept in personalized medicine, offering
immense potential to transform health care delivery and improve patient outcomes. It is …
immense potential to transform health care delivery and improve patient outcomes. It is …
Polyglutamine (PolyQ) Diseases: Navigating the Landscape of Neurodegeneration
Polyglutamine (polyQ) diseases are a group of inherited neurodegenerative disorders
caused by expanded cytosine-adenine-guanine (CAG) repeats encoding proteins with …
caused by expanded cytosine-adenine-guanine (CAG) repeats encoding proteins with …
[PDF][PDF] Big data analytics in healthcare: a review of recent advances and potential for personalized medicine
A Obijuru, JO Arowoogun, C Onwumere… - International Medical …, 2024 - researchgate.net
BIG DATA ANALYTICS IN HEALTHCARE: A REVIEW OF RECENT ADVANCES AND
POTENTIAL FOR PERSONALIZED MEDICINE Page 1 International Medical Science …
POTENTIAL FOR PERSONALIZED MEDICINE Page 1 International Medical Science …
Angiotensin system polymorphisms' in SARS-CoV-2 positive patients: assessment between symptomatic and asymptomatic patients: a pilot study
C Cafiero, F Rosapepe, R Palmirotta, A Re… - Pharmacogenomics …, 2021 - Taylor & Francis
Introduction The renin–angiotensin–aldosterone system (RAAS), a metabolic cascade
regulating pressure and circulating blood volume, has been considered the main system …
regulating pressure and circulating blood volume, has been considered the main system …
[HTML][HTML] Optimizing and accelerating the development of precision pain treatments for chronic pain: IMMPACT review and recommendations
Large variability in the individual response to even the most-efficacious pain treatments is
observed clinically, which has led to calls for a more personalized, tailored approach to …
observed clinically, which has led to calls for a more personalized, tailored approach to …
Bridging the gap between tumor-on-chip and clinics: a systematic review of 15 years of studies
Over the past 15 years, the field of oncology research has witnessed significant progress in
the development of new cell culture models, such as tumor-on-chip (ToC) systems. In this …
the development of new cell culture models, such as tumor-on-chip (ToC) systems. In this …
[HTML][HTML] Clinical perspectives of gut microbiota in patients with chronic kidney disease and end-stage kidney disease: where do we stand?
The gut microbiota (GM) plays a vital role in human health, with increasing evidence linking
its imbalance to chronic kidney disease and end-stage kidney disease. Although the exact …
its imbalance to chronic kidney disease and end-stage kidney disease. Although the exact …
[PDF][PDF] Epigenetics in neurological and psychiatric disorders: a comprehensive review of current understanding and future perspectives
The burgeoning field of epigenetics offers transformative insights into the complex
landscape of neurological and psychiatric disorders. By unraveling the intricate interplay …
landscape of neurological and psychiatric disorders. By unraveling the intricate interplay …