The polygenic architecture of schizophrenia—rethinking pathogenesis and nosology

OB Smeland, O Frei, AM Dale… - Nature Reviews …, 2020 - nature.com
Schizophrenia is a severe psychiatric disorder with considerable morbidity and mortality.
Although the past two decades have seen limited improvement in the treatment of …

Computational models in electroencephalography

K Glomb, J Cabral, A Cattani, A Mazzoni, A Raj… - Brain Topography, 2022 - Springer
Computational models lie at the intersection of basic neuroscience and healthcare
applications because they allow researchers to test hypotheses in silico and predict the …

[HTML][HTML] Active inference, stressors, and psychological trauma: A neuroethological model of (mal) adaptive explore-exploit dynamics in ecological context

A Linson, T Parr, KJ Friston - Behavioural brain research, 2020 - Elsevier
This paper offers a formal account of emotional inference and stress-related behaviour,
using the notion of active inference. We formulate responses to stressful scenarios in terms …

[HTML][HTML] Emerging methods and resources for biological interrogation of neuropsychiatric polygenic signal

E Uffelmann, D Posthuma - Biological Psychiatry, 2021 - Elsevier
Most neuropsychiatric disorders are highly polygenic, implicating hundreds to thousands of
causal genetic variants that span much of the genome. This widespread polygenicity …

Rational and translational implications of D-amino acids for treatment-resistant schizophrenia: from neurobiology to the clinics

A de Bartolomeis, L Vellucci, MC Austin, G De Simone… - Biomolecules, 2022 - mdpi.com
Schizophrenia has been conceptualized as a neurodevelopmental disorder with synaptic
alterations and aberrant cortical–subcortical connections. Antipsychotics are the mainstay of …

Perspective: Acknowledging complexity to advance the understanding of developmental coordination disorder

EJ Meachon - Frontiers in human neuroscience, 2023 - frontiersin.org
Developmental Coordination Disorder (DCD) is a heterogeneous neurodevelopmental
disorder known for primary symptoms of motor learning and execution difficulties. Recent …

Gender differential item functioning analysis in measuring computational thinking disposition among secondary school students

S Sovey, K Osman, MEEM Matore - Frontiers in Psychiatry, 2022 - frontiersin.org
Computational thinking refers to the cognitive processes underpinning the application of
computer science concepts and methodologies to the methodical approach and creation of …

[HTML][HTML] Biophysically detailed forward modeling of the neural origin of EEG and MEG signals

S Næss, G Halnes, E Hagen, DJ Hagler Jr, AM Dale… - NeuroImage, 2021 - Elsevier
Electroencephalography (EEG) and magnetoencephalography (MEG) are among the most
important techniques for non-invasively studying cognition and disease in the human brain …

The coming decade of digital brain research-a vision for neuroscience at the intersection of technology and computing

K Amunts, A Rowald, S Petkoski, MV Sanchez-Vives… - 2022 - juser.fz-juelich.de
Brain research has in recent years indisputably entered a new epoch, driven by substantial
methodological advances and digitally enabled data integration and modeling at multiple …

Computation of the electroencephalogram (EEG) from network models of point neurons

P Martínez-Cañada, TV Ness, GT Einevoll… - PLOS Computational …, 2021 - journals.plos.org
The electroencephalogram (EEG) is a major tool for non-invasively studying brain function
and dysfunction. Comparing experimentally recorded EEGs with neural network models is …