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The polygenic architecture of schizophrenia—rethinking pathogenesis and nosology
Schizophrenia is a severe psychiatric disorder with considerable morbidity and mortality.
Although the past two decades have seen limited improvement in the treatment of …
Although the past two decades have seen limited improvement in the treatment of …
Computational models in electroencephalography
Computational models lie at the intersection of basic neuroscience and healthcare
applications because they allow researchers to test hypotheses in silico and predict the …
applications because they allow researchers to test hypotheses in silico and predict the …
[HTML][HTML] Active inference, stressors, and psychological trauma: A neuroethological model of (mal) adaptive explore-exploit dynamics in ecological context
This paper offers a formal account of emotional inference and stress-related behaviour,
using the notion of active inference. We formulate responses to stressful scenarios in terms …
using the notion of active inference. We formulate responses to stressful scenarios in terms …
[HTML][HTML] Emerging methods and resources for biological interrogation of neuropsychiatric polygenic signal
Most neuropsychiatric disorders are highly polygenic, implicating hundreds to thousands of
causal genetic variants that span much of the genome. This widespread polygenicity …
causal genetic variants that span much of the genome. This widespread polygenicity …
Rational and translational implications of D-amino acids for treatment-resistant schizophrenia: from neurobiology to the clinics
A de Bartolomeis, L Vellucci, MC Austin, G De Simone… - Biomolecules, 2022 - mdpi.com
Schizophrenia has been conceptualized as a neurodevelopmental disorder with synaptic
alterations and aberrant cortical–subcortical connections. Antipsychotics are the mainstay of …
alterations and aberrant cortical–subcortical connections. Antipsychotics are the mainstay of …
Perspective: Acknowledging complexity to advance the understanding of developmental coordination disorder
EJ Meachon - Frontiers in human neuroscience, 2023 - frontiersin.org
Developmental Coordination Disorder (DCD) is a heterogeneous neurodevelopmental
disorder known for primary symptoms of motor learning and execution difficulties. Recent …
disorder known for primary symptoms of motor learning and execution difficulties. Recent …
Gender differential item functioning analysis in measuring computational thinking disposition among secondary school students
Computational thinking refers to the cognitive processes underpinning the application of
computer science concepts and methodologies to the methodical approach and creation of …
computer science concepts and methodologies to the methodical approach and creation of …
[HTML][HTML] Biophysically detailed forward modeling of the neural origin of EEG and MEG signals
Electroencephalography (EEG) and magnetoencephalography (MEG) are among the most
important techniques for non-invasively studying cognition and disease in the human brain …
important techniques for non-invasively studying cognition and disease in the human brain …
The coming decade of digital brain research-a vision for neuroscience at the intersection of technology and computing
Brain research has in recent years indisputably entered a new epoch, driven by substantial
methodological advances and digitally enabled data integration and modeling at multiple …
methodological advances and digitally enabled data integration and modeling at multiple …
Computation of the electroencephalogram (EEG) from network models of point neurons
The electroencephalogram (EEG) is a major tool for non-invasively studying brain function
and dysfunction. Comparing experimentally recorded EEGs with neural network models is …
and dysfunction. Comparing experimentally recorded EEGs with neural network models is …