Osteoporosis is a prevalent bone disease of the aging population, which is characterized by
a decrease in bone mass because of the imbalance of bone metabolism. Although the …

Matrine is an alkaloid isolated from the traditional Chinese medicine Sophora flavescens
Aiton. At present, a large number of studies have proved that matrine has an anticancer …

Osteoporosis is caused by an osteoclast activation mechanism. People suffering from
osteoporosis are prone to bone defects. Increasing evidence indicates that scavenging …

Pathological cardiac fibrosis is a common feature in multiple cardiovascular diseases that
contributes to the occurrence of heart failure and life-threatening arrhythmias. Our previous …

Ethnopharmacological relevance “Dogel ebs” was known as Sophora flavescens Ait., which
has been widely utilized in the clinical practice of traditional Chinese Mongolian herbal …

Matrine (MT) is a naturally occurring alkaloid and an bioactive component of Chinese herbs,
such as Sophora flavescens and Radix Sophorae tonkinensis. Emerging evidence suggests …

Osteoporosis bone defect is a refractory orthopaedic disease which characterized by
impaired bone quality and bone regeneration capacity. Current therapies, including …

Lung cancer, renowned for its fast progression and metastatic potency, is rising to become a
leading cause of death globally. It has been long observed that lung cancer is particularly …

Background Osteolytic diseases share symptoms such as bone loss, fracture and pain,
which are caused by over-activated osteoclasts. Targeting osteoclast differentiation has …

Psoralea corylifolia (P corylifolia) has been popularly applied in traditional Chinese
medicine decoction for treating osteoporosis and promoting fracture healing since centuries …