Owing to their outstanding performances in molecular recognition, antibodies are
extensively used in research and applications in molecular biology, biotechnology and …

The development of allergic disease involves the production of IgE antibodies upon allergen
exposure in a process called sensitization. IgE binds to receptors on the surface of mast …

We propose a computational investigation on the interaction mechanisms between SARS-
CoV-2 spike protein and possible human cell receptors. In particular, we make use of our …

B-cells can neutralize pathogenic molecules by targeting them with extreme specificity using
receptors secreted or expressed on their surface (antibodies). This is achieved via molecular …

Antibodies represent essential tools in research and diagnostics and are rapidly growing in
importance as therapeutics. Commonly used methods to obtain novel antibodies typically …

Despite the huge effort to contain the infection, the novel SARS-CoV-2 coronavirus has
rapidly become pandemic, mainly due to its extremely high human-to-human transmission …

Although antibodies have become the fastest-growing class of therapeutics on the market, it
is still challenging to develop them for therapeutic applications, which often require these …

Detection of protein structure similarity is a central challenge in structural bioinformatics.
Comparisons are usually performed at the polypeptide chain level, however the functional …

Due to their shared genetic history, antibodies from the same clonotype often bind to the
same epitope. This knowledge is used in immune repertoire mining, where known binders …

We present a method for efficiently and effectively assessing whether and where two
proteins can interact with each other to form a complex. This is still largely an open problem …