The pharmacological activities of licorice

R Yang, L Wang, B Yuan, Y Liu - Planta medica, 2015 - thieme-connect.com
Licorice is one of the oldest and most frequently used herbs in traditional Chinese medicine.
It contains more than 20 triterpenoids and 300 flavonoids. In recent years, a lot of studies …

Molecular mechanisms underlying the anticancer activities of licorice flavonoids

Z Zhang, L Yang, J Hou, S Tian, Y Liu - Journal of Ethnopharmacology, 2021 - Elsevier
Ethnopharmacological relevance Licorice has been commonly used in traditional Chinese
medicine for treatment of gastric, liver, and respiratory disease conditions for more than two …

SDTNBI: an integrated network and chemoinformatics tool for systematic prediction of drug–target interactions and drug repositioning

Z Wu, F Cheng, J Li, W Li, G Liu… - Briefings in …, 2017 - academic.oup.com
Computational prediction of drug–target interactions (DTIs) and drug repositioning provides
a low-cost and high-efficiency approach for drug discovery and development. The traditional …

[HTML][HTML] Transient receptor potential vanilloid type-1 channel regulates diet-induced obesity, insulin resistance, and leptin resistance

E Lee, DY Jung, JH Kim, PR Patel, X Hu… - The FASEB …, 2015 - pmc.ncbi.nlm.nih.gov
Insulin resistance is a major characteristic of obesity and type 2 diabetes, but the underlying
mechanism is unclear. Recent studies have shown a metabolic role of capsaicin that may be …

A systematic review of the anticancer properties of compounds isolated from Licorice (Gancao)

ZH Tang, T Li, YG Tong, XJ Chen, XP Chen… - Planta …, 2015 - thieme-connect.com
Licorice (Gancao in Chinese) has been used worldwide as a botanical source in medicine
and as a sweetening agent in food products for thousands of years. Triterpene saponins and …

Licorice (Glycyrrhiza glabra L.)-derived phytochemicals target multiple signaling pathways to confer oncopreventive and oncotherapeutic effects

HS Tuli, VK Garg, JK Mehta, G Kaur… - OncoTargets and …, 2022 - pmc.ncbi.nlm.nih.gov
Cancer is a highly lethal disease, and its incidence has rapidly increased worldwide over
the past few decades. Although chemotherapeutics and surgery are widely used in clinical …

Identification of CDK2 as a novel target in treatment of prostate cancer

X Yin, J Yu, Y Zhou, C Wang, Z Jiao, Z Qian… - Future …, 2018 - Taylor & Francis
Aim: This study aims the potential gene involved in the metastasis of prostate cancer (Pca).
Methods: PubMed GEO datasets (GSE6605 and GSE6606) were downloaded. We used …

Effects of nanoplastic exposure on the growth performance and molecular characterization of growth-associated genes in juvenile Macrobrachium nipponense

Y Li, X Du, Q Jiang, Y Huang, Y Zhao - … and Physiology Part C: Toxicology & …, 2022 - Elsevier
Nanoplastic pollution has become a major issue in the aquatic environment while there are
few studies examined the effects of nanoplastic exposure on crustaceans. To investigate this …

Purification and characterization of a novel β-glucuronidase precisely converts glycyrrhizin to glycyrrhetinic acid 3-O-mono-β-D-glucuronide from plant endophytic …

Q Zhang, B Gao, Y **ao, H Yang, Y Wang, L Du… - International Journal of …, 2020 - Elsevier
Glycyrrhetinic acid monoglucuronide (GAMG) is an innovative functional sweetener with
higher sweetness and stronger pharmacological activity than glycyrrhizin (GL). A novel β …

Molecular basis of prostate cancer and natural products as potential chemotherapeutic and chemopreventive agents

B Bai, Q Chen, R **g, X He, H Wang, Y Ban… - Frontiers in …, 2021 - frontiersin.org
Prostate cancer is the second most common malignant cancer in males. It involves a
complex process driven by diverse molecular pathways that closely related to the survival …