In 1979, just 8 years after Godfrey Hounsfield's introduction of CT, Leon Axel first proposed a
method for determining tissue perfusion from dynamic contrast enhanced CT data [1]. Due to …

Perfusion CT is a technique that can be readily incorporated into the existing CT protocols
that continue to provide the mainstay for anatomical imaging in oncology to provide an in …

Dynamic contrast-enhanced computed tomography (DCE-CT) assesses the vascular
support of tumours through analysis of temporal changes in attenuation in blood vessels and …

Tumor angiogenesis is the process by which new blood vessels are formed from the existing
vessels in a tumor to promote tumor growth (1). Although angiogenesis is essential for tumor …

Functional Computed Tomography (CT) describes the use of existing technologies and
conventional contrast agents to capture physiological parameters that reflect the vasculature …

One novel approach of transporting drugs into the central nervous system (CNS) involves
the activation of receptors on the endothelial cells comprising the blood brain barrier (BBB) …

Labradimil (Cereport®; also formerly referred to as RMP-7) is a 9-amino-acid peptide
designed for selectivity for the bradykinin B 2 receptor and a longer plasma half-life than …

Purpose: Structural CT criteria such as nodal size and appearance have a poor correlation
with the grade and activity of a lymphoma mass. This study investigates the potential for …

Background Nitric oxide has been implicated in tumour angiogenesis and in the maintaining
of vasodilator tone of tumour blood vessels. The tumour vascular effects of inhibition of nitric …

Focusing on anatomy and procedural strategy for perfusion CT imaging in clinical neurology
and cerebrovascular disease, this new text-atlas combines pictures and schematic diagrams …