Life in living organisms is dependent on specific and purposeful interaction between other
molecules. Such purposeful interactions make the various processes inside the cells and the …

Heart development in mammalian systems is controlled by combinatorial interactions of
master cardiac transcription factors such as TBX5 and NKX2. 5. They bind to …

Here, we have investigated the possible effect of UV-B light on the folding/unfolding
properties and stability of Arabidopsis thaliana MYB4 (AtMYB4) transcription factor in vitro by …

Viruses are a diverse biological group capable of infecting several hosts such as bacteria,
plants, and animals, including humans. Viral infections constitute a threat to the human …

DNA ligases join adjacent 5′ phosphate (5′ P) and 3′ hydroxyl (3′ OH) termini of
double-stranded DNA via a three-step mechanism requiring a nucleotide cofactor and …

DNA ligases join breaks in the phosphodiester backbone of DNA by catalysing the formation
of bonds between opposing 5′ P and 3′ OH ends in an adenylation-dependent manner …

Iron is an essential nutrient for bacteria, however its propensity to form toxic hydroxyl
radicals at high intracellular concentrations, requires its acquisition to be tightly regulated …

Forkhead transcription factor C2 (FOXC2) is a transcription factor regulating vascular and
lymphatic development, and its mutations are linked to lymphedema-distichiasis syndrome …

The discovery and studies of cancer stem cells population shed light on the recurrence and
invasive mechanisms of the malignant tumor. As the culprit of the malignancy, cancer stems …

The purpose of my doctoral studies has been the development of bioinformatics methods to
quantitatively evaluate associations between proteins and nucleic acids (NAs). This thesis …