COVID-19, cytokines, inflammation, and spices: How are they related?

AB Kunnumakkara, V Rana, D Parama, K Banik… - Life sciences, 2021 - Elsevier
Background Cytokine storm is the exaggerated immune response often observed in viral
infections. It is also intimately linked with the progression of COVID-19 disease as well as …

Ethnopharmacological, phytochemical and clinical studies on Fenugreek (Trigonella foenum-graecum L.)

N Singh, SS Yadav, S Kumar, B Narashiman - Food Bioscience, 2022 - Elsevier
Trigonella foenum-graecum (fenugreek) belonging to the family Fabaceae, is widely used
for both culinary as well as clinical purposes since antiquity. Folkloric medicines across …

Retinal neuroprotective effects of quercetin in streptozotocin-induced diabetic rats

B Kumar, SK Gupta, TC Nag, S Srivastava… - Experimental Eye …, 2014 - Elsevier
The aim of the present study was to evaluate the effects of Quercetin (Qctn), a plant based
flavonol, on retinal oxidative stress, neuroinflammation and apoptosis in streptozotocin …

[HTML][HTML] Update on the effects of antioxidants on diabetic retinopathy: In vitro experiments, animal studies and clinical trials

JJ Garcia-Medina, E Rubio-Velazquez… - Antioxidants, 2020 - mdpi.com
Current therapies for diabetic retinopathy (DR) incorporate blood glucose and blood
pressure control, vitrectomy, photocoagulation, and intravitreal injections of anti-vascular …

Does fenugreek (Trigonella foenum-graecum) seed improve inflammation, and oxidative stress in patients with type 2 diabetes mellitus? A parallel group randomized …

R Tavakoly, MR Maracy, M Karimifar… - European Journal of …, 2018 - Elsevier
Introduction Fenugreek seed has not previously been investigated for its effect on oxidative
stress and inflammation in human subjects. The aim of this study was to examine the effects …

Cardioprotective effects of Fenugreek (Trigonella foenum-graceum) seed extract in streptozotocin induced diabetic rats

S Bafadam, M Mahmoudabady… - Journal of …, 2021 - pmc.ncbi.nlm.nih.gov
Introduction: Inadequate control of diabetes mellitus (DM) leads to considerable
cardiovascular implications like diabetic cardiomyopathy (DCM). Cardiomyocyte apoptosis …

The role of natural products in diabetic retinopathy

Y Zhao, Y Chen, N Yan - Biomedicines, 2024 - mdpi.com
Diabetic retinopathy (DR) is one of the most severe complications of diabetes mellitus and
potentially leads to significant visual impairment and blindness. The complex mechanisms …

Natural plant medications for the treatment of retinal diseases: The blood-retinal barrier as a clue

Y Ren, H Liang, M **e, M Zhang - Phytomedicine, 2024 - Elsevier
Background Retinal diseases significantly contribute to the global burden of visual
impairment and blindness. The occurrence of retinal diseases is often accompanied by …

Herbal medicine for ocular diseases: An age old therapy and its future perspective

AS Pokkalath, A Sawant, SP Sawarkar - Journal of Drug Delivery Science …, 2022 - Elsevier
Herbal medicines have been quintessential elements of therapeutic systems for ocular
ailments in many ancient civilizations. The current invasive and non-invasive treatment …

Neuropeptides, trophic factors, and other substances providing morphofunctional and metabolic protection in experimental models of diabetic retinopathy

K Szabadfi, E Pinter, D Reglodi, R Gabriel - International review of cell and …, 2014 - Elsevier
Vision is the most important sensory modality for many species, including humans. Damage
to the retina results in vision loss or even blindness. One of the most serious complications …