[HTML][HTML] Simulation-based approaches for drug delivery systems: Navigating advancements, opportunities, and challenges
I Salahshoori, M Golriz, MAL Nobre, S Mahdavi… - Journal of Molecular …, 2024 - Elsevier
Efficient drug delivery systems (DDSs) play a pivotal role in ensuring pharmaceuticals'
targeted and effective administration. However, the intricate interplay between drug …
targeted and effective administration. However, the intricate interplay between drug …
Nasal drug delivery devices: characteristics and performance in a clinical perspective—a review
PG Djupesland - Drug delivery and translational research, 2013 - Springer
Nasal delivery is the logical choice for topical treatment of local diseases in the nose and
paranasal sinuses such as allergic and non-allergic rhinitis and sinusitis. The nose is also …
paranasal sinuses such as allergic and non-allergic rhinitis and sinusitis. The nose is also …
The nasal approach to delivering treatment for brain diseases: an anatomic, physiologic, and delivery technology overview
PG Djupesland, JC Messina, RA Mahmoud - Therapeutic delivery, 2014 - Taylor & Francis
The intricate pathophysiology of brain disorders, difficult access to the brain, and the
complexity and high risks and costs of drug development represent major hurdles for …
complexity and high risks and costs of drug development represent major hurdles for …
Computational characterization of inhaled droplet transport to the nasopharynx
S Basu - Scientific Reports, 2021 - nature.com
How human respiratory physiology and the transport phenomena associated with inhaled
airflow in the upper airway proceed to impact transmission of SARS-CoV-2, leading to the …
airflow in the upper airway proceed to impact transmission of SARS-CoV-2, leading to the …
[LIBRO][B] Multiphase flow handbook
E Michaelides, CT Crowe, JD Schwarzkopf - 2016 - books.google.com
The Multiphase Flow Handbook, Second Edition is a thoroughly updated and reorganized
revision of the late Clayton Crowe's work, and provides a detailed look at the basic concepts …
revision of the late Clayton Crowe's work, and provides a detailed look at the basic concepts …
[LIBRO][B] Computational fluid and particle dynamics in the human respiratory system
Traditional research methodologies in the human respiratory system have always been
challenging due to their invasive nature. Recent advances in medical imaging and …
challenging due to their invasive nature. Recent advances in medical imaging and …
Mechanics of airflow in the human nasal airways
DJ Doorly, DJ Taylor, RC Schroter - Respiratory physiology & neurobiology, 2008 - Elsevier
The mechanics of airflow in the human nasal airways is reviewed, drawing on the findings of
experimental and computational model studies. Modelling inevitably requires simplifications …
experimental and computational model studies. Modelling inevitably requires simplifications …
How to characterize a nasal product. The state of the art of in vitro and ex vivo specific methods
Nasal delivery offers many benefits over other conventional routes of delivery (eg oral or
intravenous administration). Benefits include, among others, a fast onset of action, non …
intravenous administration). Benefits include, among others, a fast onset of action, non …
Effects of surface smoothness on inertial particle deposition in human nasal models
Computational fluid dynamics (CFD) predictions of inertial particle deposition have not
compared well with data from nasal replicas due to effects of surface texture and the …
compared well with data from nasal replicas due to effects of surface texture and the …
Detailed micro-particle deposition patterns in the human nasal cavity influenced by the breathing zone
The breathing region connects the nasal cavity with the outside environmental air where
flow is accelerated through the nostrils. Particles introduced into the nasal cavity without …
flow is accelerated through the nostrils. Particles introduced into the nasal cavity without …