We review the considerable progress during the recent decade in the endeavours of
designing, optimising, and utilising carrier particle systems for structural and functional …

Complex integral membrane proteins, which are embedded in the cell surface lipid bilayer
by multiple transmembrane spanning polypeptides, encompass families of proteins that are …

Despite remarkable progress, mainly due to the development of LCP and
'bicelle'crystallization, lack of structural information remains a bottleneck in membrane …

Although polymer-based lipid nanodiscs are increasingly used in the structural studies of
membrane proteins, the charge of the belt-forming polymer is a major limitation for functional …

G-protein-coupled receptors (GPCRs) are the largest family of membrane proteins, regulate
a plethora of physiological responses and are the therapeutic target for 30–40% of clinically …

Styrene‐maleic acid copolymers (SMAs), and related amphiphilic copolymers, are promising
tools for isolating and studying integral membrane proteins in a native‐like state. However …

Different amphiphilic co-polymers have been introduced to produce polymer–lipid particles
with nanodisc structure composed of an inner lipid bilayer and polymer chains self …

The article briefly reviews the history of the development of ideas about the dynamics of
proteins and other biopolymers and notes the significant contribution of VI Goldansky in …

Integral membrane proteins are critical for many cellular functions. Roughly 25% of all
human genes code for membrane proteins, and about 70% of all approved drugs target …

Structural studies require the production of target proteins in large quantities and with a high
degree of purity. For membrane proteins, the bottleneck in determining their structure is the …