Background: Analysis of the human connectome using functional magnetic resonance
imaging (fMRI) started in the mid-1990s and attracted increasing attention in attempts to …

Middle age has historically been an understudied period of life compared to older age, when
cognitive and brain health decline are most pronounced, but the scope for intervention may …

A central goal in systems neuroscience is the parcellation of the cerebral cortex into discrete
neurobiological “atoms”. Resting-state functional magnetic resonance imaging (rs-fMRI) …

The imprecise nature of psychiatric nosology restricts progress towards characterizing and
treating mental health disorders. One issue is the 'heterogeneity problem': different causal …

Over the past decade there has been an enormous rise in the application of functional and
structural connectivity approaches to explore the brain's intrinsic organization in healthy and …

Modelling the human brain as a complex network has provided a powerful mathematical
framework to characterize the structural and functional architectures of the brain. In the past …

The development of human cognition results from the emergence of coordinated activity
between distant brain areas. Network science, combined with non-invasive functional …

Healthy aging has been associated with decreased specialization in brain function. This
characterization has focused largely on describing age-accompanied differences in …

At rest, the brain's sensorimotor and higher cognitive systems engage in organized patterns
of correlated activity forming resting-state networks. An important empirical question is how …

Cognitive function is driven by dynamic interactions between large-scale neural circuits or
networks, enabling behaviour. However, fundamental principles constraining these dynamic …