Epidemiology, diagnosis, and antimicrobial treatment of acute bacterial meningitis

MC Brouwer, AR Tunkel… - Clinical microbiology …, 2010 - journals.asm.org
The epidemiology of bacterial meningitis has changed as a result of the widespread use of
conjugate vaccines and preventive antimicrobial treatment of pregnant women. Given the …

Dilemmas in the diagnosis of acute community-acquired bacterial meningitis

MC Brouwer, GE Thwaites, AR Tunkel, D van de Beek - The Lancet, 2012 - thelancet.com
Rapid diagnosis and treatment of acute community-acquired bacterial meningitis reduces
mortality and neurological sequelae, but can be delayed by atypical presentation …

ESCMID guideline: diagnosis and treatment of acute bacterial meningitis

D Van de Beek, C Cabellos… - Clinical …, 2016 - clinicalmicrobiologyandinfection …
Bacterial meningitis is a severe infectious disease of the membranes lining the brain
resulting in a high mortality and morbidity throughout the world. In the past decades the …

Clinical prediction rule for identifying children with cerebrospinal fluid pleocytosis at very low risk of bacterial meningitis

LE Nigrovic, N Kuppermann, CG Macias… - Jama, 2007 - jamanetwork.com
ContextChildren with cerebrospinal fluid (CSF) pleocytosis are routinely admitted to the
hospital and treated with parenteral antibiotics, although few have bacterial meningitis. We …

Effect of antibiotic pretreatment on cerebrospinal fluid profiles of children with bacterial meningitis

LE Nigrovic, R Malley, CG Macias, JT Kanegaye… - …, 2008 - publications.aap.org
OBJECTIVE. The goal of this study was to evaluate the effect of antibiotic administration
before lumbar puncture on cerebrospinal fluid profiles in children with bacterial meningitis …

Diagnosis and treatment of central nervous system infections in the emergency department

M Dorsett, SY Liang - Emergency Medicine Clinics, 2016 - emed.theclinics.com
A key clinical responsibility of the emergency physician is to consider the “worst case
scenario” for a given chief complaint. When it comes to infections of the central nervous …

Serum procalcitonin level and other biological markers to distinguish between bacterial and aseptic meningitis in children: a European multicenter case cohort study

F Dubos, B Korczowski, DA Aygun… - … of pediatrics & …, 2008 - jamanetwork.com
Objective To validate procalcitonin (PCT) level as the best biological marker to distinguish
between bacterial and aseptic meningitis in children in the emergency department. Design …

Management of acute bacterial meningitis in children

Z Alamarat, R Hasbun - Infection and drug resistance, 2020 - Taylor & Francis
Acute community-acquired bacterial meningitis (ABM) in children continues to have high
rates of neurological morbidity and mortality despite the overall declining rates of infection …

Aseptic meningitis

BE Lee, HD Davies - Current opinion in infectious diseases, 2007 - journals.lww.com
Enteroviruses are the major causes of aseptic meningitis. The major focus of diagnosis
remains ruling out bacterial infection or confirming enteroviral etiology of infection. Properly …

Emergency diagnosis and treatment of adult meningitis

MT Fitch, D van de Beek - The Lancet infectious diseases, 2007 - thelancet.com
Despite the existence of antibiotic therapies against acute bacterial meningitis, patients with
the disease continue to suffer significant morbidity and mortality in both high and low-income …