Structure and dynamics of GPCRs in lipid membranes: physical principles and experimental approaches

AJY Jones, F Gabriel, A Tandale, D Nietlispach - Molecules, 2020 - mdpi.com
Over the past decade, the vast amount of information generated through structural and
biophysical studies of GPCRs has provided unprecedented mechanistic insight into the …

Analysis of corrosion inhibition of Kleinhovia hospita plant extract aided by quantification of hydrogen evolution using a GLCM/SVM method

F Gapsari, DB Darmadi, PH Setyarini, H Wijaya… - International Journal of …, 2023 - Elsevier
During a corrosion inhibition test, a combination of common electrochemical corrosion test
methods with an in-situ quantification of H 2 evolution could provide a comprehensive …

Keratan sulfate, an electrosensory neurosentient bioresponsive cell instructive glycosaminoglycan

J Melrose - Glycobiology, 2024 - academic.oup.com
The roles of keratan sulfate (KS) as a proton detection glycosaminoglycan in neurosensory
processes in the central and peripheral nervous systems is reviewed. The functional …

Triglyceride-tethered membrane lipase sensor

UM Lankage, SA Holt, S Bridge, B Cornell… - … Applied Materials & …, 2023 - ACS Publications
Sensors that can quickly measure the lipase activity from biological samples are useful in
enzyme production and medical diagnostics. However, current lipase sensors have …

Binding of DNA origami to lipids: maximizing yield and switching via strand displacement

JKD Singh, E Darley, P Ridone, JP Gaston… - Nucleic acids …, 2021 - academic.oup.com
Liposomes are widely used as synthetic analogues of cell membranes and for drug delivery.
Lipid-binding DNA nanostructures can modify the shape, porosity and reactivity of …

Interfacial approach to fabricate covalently and noncovalently attached inverse-phosphocholine supported lipid bilayers on TiO2 and SiO2 surfaces

TN Sut, S Meker, DJ Koo, JA Jackman… - Journal of Industrial and …, 2023 - Elsevier
Inverse-phosphocholine lipids such as DOCP are intriguing biomolecules for surface
functionalization because they can form supported lipid bilayers (SLBs) on titania surfaces …

Physical chemistry of chloroquine permeation through the cell membrane with atomistic detail

M Paulikat, GM Piccini, E Ippoliti… - Journal of Chemical …, 2023 - ACS Publications
We provide a molecular-level description of the thermodynamics and mechanistic aspects of
drug permeation through the cell membrane. As a case study, we considered the antimalaria …

Electro‐Stimulation, a Promising Therapeutic Treatment Modality for Tissue Repair: Emerging Roles of Sulfated Glycosaminoglycans as Electro‐Regulatory Mediators …

AJ Hayes, J Melrose - Advanced Therapeutics, 2020 - Wiley Online Library
Glycosaminoglycans (GAGs) are a family of diverse biomolecules that decorate
proteoglycans in the glycocalyx and extracellular matrix of all cells. They exist as linear …

Aryl urea substituted fatty acids: a new class of protonophoric mitochondrial uncoupler that utilises a synthetic anion transporter

T Rawling, H MacDermott-Opeskin, A Roseblade… - Chemical …, 2020 - pubs.rsc.org
Respiring mitochondria establish a proton gradient across the mitochondrial inner
membrane (MIM) that is used to generate ATP. Protein-independent mitochondrial …

A mechanoelastic glimpse on hyaluronan-coated extracellular vesicles

D Paul, A Paul, D Mukherjee, S Saroj… - The Journal of …, 2022 - ACS Publications
Cancer cells secrete extracellular vesicles (EVs) covered with a carbohydrate polymer,
hyaluronan (HA), linked to tumor malignancy. Herein, we have unravelled the contour …