[HTML][HTML] Where is the error? Hierarchical predictive coding through dendritic error computation

FA Mikulasch, L Rudelt, M Wibral… - Trends in Neurosciences, 2023 - cell.com
Top-down feedback in cortex is critical for guiding sensory processing, which has
prominently been formalized in the theory of hierarchical predictive coding (hPC). However …

Volume electron microscopy

CJ Peddie, C Genoud, A Kreshuk, K Meechan… - Nature Reviews …, 2022 - nature.com
Life exists in three dimensions, but until the turn of the century most electron microscopy
methods provided only 2D image data. Recently, electron microscopy techniques capable of …

Neuronal wiring diagram of an adult brain

S Dorkenwald, A Matsliah, AR Sterling, P Schlegel… - Nature, 2024 - nature.com
Connections between neurons can be mapped by acquiring and analysing electron
microscopic brain images. In recent years, this approach has been applied to chunks of …

The connectome of an insect brain

M Winding, BD Pedigo, CL Barnes, HG Patsolic, Y Park… - Science, 2023 - science.org
Brains contain networks of interconnected neurons and so knowing the network architecture
is essential for understanding brain function. We therefore mapped the synaptic-resolution …

A connectomic study of a petascale fragment of human cerebral cortex

A Shapson-Coe, M Januszewski, DR Berger, A Pope… - BioRxiv, 2021 - biorxiv.org
We acquired a rapidly preserved human surgical sample from the temporal lobe of the
cerebral cortex. We stained a 1 mm3 volume with heavy metals, embedded it in resin, cut …

[HTML][HTML] Reconstruction of neocortex: Organelles, compartments, cells, circuits, and activity

NL Turner, T Macrina, JA Bae, R Yang, AM Wilson… - Cell, 2022 - cell.com
We assembled a semi-automated reconstruction of L2/3 mouse primary visual cortex from∼
250× 140× 90 μm 3 of electron microscopic images, including pyramidal and non-pyramidal …

Sustained deep-tissue voltage recording using a fast indicator evolved for two-photon microscopy

Z Liu, X Lu, V Villette, Y Gou, KL Colbert, S Lai, S Guan… - Cell, 2022 - cell.com
Genetically encoded voltage indicators are emerging tools for monitoring voltage dynamics
with cell-type specificity. However, current indicators enable a narrow range of applications …

Microglia rescue neurons from aggregate-induced neuronal dysfunction and death through tunneling nanotubes

H Scheiblich, F Eikens, L Wischhof, S Opitz, K Jüngling… - Neuron, 2024 - cell.com
Microglia are crucial for maintaining brain health and neuron function. Here, we report that
microglia establish connections with neurons using tunneling nanotubes (TNTs) in both …

Neuroscience needs network science

DL Barabási, G Bianconi, E Bullmore… - Journal of …, 2023 - Soc Neuroscience
The brain is a complex system comprising a myriad of interacting neurons, posing significant
challenges in understanding its structure, function, and dynamics. Network science has …

Neuronal parts list and wiring diagram for a visual system

A Matsliah, SC Yu, K Kruk, D Bland, AT Burke, J Gager… - Nature, 2024 - nature.com
A catalogue of neuronal cell types has often been called a 'parts list'of the brain, and
regarded as a prerequisite for understanding brain function,. In the optic lobe of Drosophila …