[HTML][HTML] Novel advances in inhibiting advanced glycation end product formation using natural compounds

Q Song, J Liu, L Dong, X Wang, X Zhang - Biomedicine & Pharmacotherapy, 2021‏ - Elsevier
Advanced glycation end products (AGEs) are a group of complex compounds generated by
nonenzymatic interactions between proteins and reducing sugars or lipids. AGEs …

Targeting aging mechanisms: pharmacological perspectives

A Moskalev, Z Guvatova, IDA Lopes, CW Beckett… - Trends in Endocrinology …, 2022‏ - cell.com
Geroprotectors slow down aging and promote healthy longevity in model animals. Although
hundreds of compounds have been shown to extend the life of laboratory model organisms …

Advanced glycation end products in health and disease

VP Reddy, P Aryal, EK Darkwah - Microorganisms, 2022‏ - mdpi.com
Advanced glycation end products (AGEs), formed through the nonenzymatic reaction of
reducing sugars with the side-chain amino groups of lysine or arginine of proteins, followed …

[HTML][HTML] Physiology and pathophysiology of carnosine

AA Boldyrev, G Aldini, W Derave - Physiological reviews, 2013‏ - journals.physiology.org
Abstract Carnosine (β-alanyl-l-histidine) was discovered in 1900 as an abundant non-
protein nitrogen-containing compound of meat. The dipeptide is not only found in skeletal …

Baking, ageing, diabetes: a short history of the Maillard reaction

M Hellwig, T Henle - Angewandte Chemie International Edition, 2014‏ - Wiley Online Library
The reaction of reducing carbohydrates with amino compounds described in 1912 by Louis‐
Camille Maillard is responsible for the aroma, taste, and appearance of thermally processed …

[HTML][HTML] Metal pollutants and cardiovascular disease: mechanisms and consequences of exposure

NV Solenkova, JD Newman, JS Berger, G Thurston… - American heart …, 2014‏ - Elsevier
Introduction There is epidemiological evidence that metal contaminants may play a role in
the development of atherosclerosis and its complications. Moreover, a recent clinical trial of …

Uremic toxicity of advanced glycation end products in CKD

AEM Stinghen, ZA Massy, H Vlassara… - Journal of the …, 2016‏ - journals.lww.com
Advanced glycation end products (AGEs), a heterogeneous group of compounds formed by
nonenzymatic glycation reactions between reducing sugars and amino acids, lipids, or DNA …

Dicarbonyls and advanced glycation end-products in the development of diabetic complications and targets for intervention

S Brings, T Fleming, M Freichel… - International journal of …, 2017‏ - mdpi.com
Advanced glycation end-products (AGEs) are non-enzymatic protein and amino acid
adducts as well as DNA adducts which form from dicarbonyls and glucose. AGE formation is …

Advanced glycation end products: potential mechanism and therapeutic target in cardiovascular complications under diabetes

P Yang, J Feng, Q Peng, X Liu… - Oxidative Medicine and …, 2019‏ - Wiley Online Library
The occurrence and development of cardiovascular complications are predominantly
responsible for the increased morbidity and mortality observed in patients with diabetes …

Advanced glycation end products mediated cellular and molecular events in the pathology of diabetic nephropathy

A Kumar Pasupulati, PS Chitra, GB Reddy - Biomolecular concepts, 2016‏ - degruyter.com
Diabetic nephropathy (DN) is a major cause of morbidity and mortality in diabetic patients
and a leading cause of end-stage renal disease (ESRD). Degenerative changes such as …