Understanding how chromatin is organized within the nucleus and how this 3D architecture
influences gene regulation, cell fate decisions and evolution are major questions in cell …

Recent outbreaks of food-borne diseases highlight the need for reducing bacterial
pathogens in foods of animal origin. Animal enteric pathogens are a direct source for food …

MicroRNAs (miRNAs) are small noncoding regulatory RNAs that reduce stability and/or
translation of fully or partially sequence-complementary target mRNAs. In order to identify …

The field of molecular evolution has experienced explosive growth in recent years due to the
rapid accumulation of genetic sequence data, continuous improvements to computer …

Decrypting the rearrangements that drive mammalian chromosome evolution is critical to
understanding the molecular bases of speciation, adaptation, and disease susceptibility …

The precise pattern and timing of speciation events that gave rise to all living placental
mammals remain controversial. We provide a comprehensive phylogenetic analysis of …

Most land plants are now known to be ancient polyploids that have rediploidized.
Diploidization involves many changes in genome organization that ultimately restore …

Our basic question is: Given a collection of DNA sequences, what underlying forces are
responsible for the observed patterns of variability? To approach this question we introduce …

The Genome 10K Project was established in 2009 by a consortium of biologists and
genome scientists determined to facilitate the sequencing and analysis of the complete …

Compared with other mammals, the genomes of humans and other primates show an
enrichment of large, interspersed segmental duplications (SDs) with high levels of sequence …