The gastrointestinal tract is the only internal organ to have evolved with its own independent
nervous system, known as the enteric nervous system (ENS). This Review provides an …

Proteases are signaling molecules that specifically control cellular functions by cleaving
protease-activated receptors (PARs). The four known PARs are members of the large family …

Covers all aspects of the structure, function, neurochemistry, transmitter identification and
development of the enteric nervous system This book brings together extensive knowledge …

Background The role of intestinal microbiota in the development and function of host
physiology is of high interest, especially with respect to the nervous system. While strong …

Probiotics are live non‐pathogenic commensal organisms that exert therapeutic effects in
travellers' diarrhea, irritable bowel syndrome and inflammatory bowel disease. Little is …

▪ Abstract The enteric nervous system exerts local control over mixing and propulsive
movements in the small intestine. When digestion is in progress, intrinsic primary afferent …

The application of 5‐HT to the gut elicits a wide variety of effects because of the expression
and wide distribution in the bowel of many subtypes of 5‐HT. There is, however, no reason …

Intrinsic primary afferent neurons (IPANs) of the enteric nervous system are quite different
from all other peripheral neurons. The IPANs are transducers of physiological stimuli …

After a long period of inconclusive observations, the intrinsic primary afferent neurons of the
intestine have been identified. The intestine is thus equipped with two groups of afferent …

The guinea‐pig small intestine has been very widely used to study the physiology,
pharmacology and morphology of the enteric nervous system. It also provides an ideal …