Fish are the most diversified group of vertebrates and, although progress has been made in
the past years, only relatively few fish species have been examined to date, with regards to …

Mammalian studies have shaped our understanding of the endocrine control of appetite and
body weight in vertebrates and provided the basic vertebrate model that involves central …

We summarize the biological impact of leptin signaling as well as the molecular and cellular
characteristics of leptin action. Our focus is principally in the central nervous system and we …

The regulation of food intake in fish is a complex process carried out through several
different mechanisms in the central nervous system (CNS) with hypothalamus being the …

Endocrine factors regulate food intake and growth, two interlinked physiological processes
critical for the proper development of organisms. Somatic growth is mainly regulated by …

The environment which living organisms inhabit is not constant and many factors, such as
light, temperature, and food availability, display cyclic and predictable variations. To adapt to …

Lipid storage is an evolutionary conserved process that exists in all organisms from simple
prokaryotes to humans. In Metazoa, long-term lipid accumulation is restricted to specialized …

Spexin (SPX) is a neuropeptide identified recently by bioinformatic approach. At present not
much is known about its biological actions, and comparative studies of SPX in …

Leptin, the product of the obese (ob or Lep) gene, was first cloned in teleost fish in 2005,
more than a decade after its identification in mammals. This was because bony fish and …

Evidence indicates that central regulation of food intake is well conserved along the
vertebrate lineage, at least between teleost fish and mammals. However, several differences …