Silencing and transcriptional regulation of endogenous retroviruses: an overview
FK Geis, SP Goff - Viruses, 2020 - mdpi.com
Almost half of the human genome is made up of transposable elements (TEs), and about 8%
consists of endogenous retroviruses (ERVs). ERVs are remnants of ancient exogenous …
consists of endogenous retroviruses (ERVs). ERVs are remnants of ancient exogenous …
Molecular physiology of Arc/Arg3. 1: The oligomeric state hypothesis of synaptic plasticity
MS Eriksen, CR Bramham - Acta Physiologica, 2022 - Wiley Online Library
The immediate early gene, Arc, is a pivotal regulator of synaptic plasticity, memory, and
cognitive flexibility. But what is Arc protein? How does it work? Inside the neuron, Arc is a …
cognitive flexibility. But what is Arc protein? How does it work? Inside the neuron, Arc is a …
Intercellular communication in the nervous system goes viral
Viruses and transposable elements are major drivers of evolution and make up over half the
sequences in the human genome. In some cases, these elements are co-opted to perform …
sequences in the human genome. In some cases, these elements are co-opted to perform …
Arc self‐association and formation of virus‐like capsids are mediated by an N‐terminal helical coil motif
Activity‐regulated cytoskeleton‐associated protein (Arc) is a protein interaction hub with
diverse roles in intracellular neuronal signaling, and important functions in neuronal …
diverse roles in intracellular neuronal signaling, and important functions in neuronal …
Structure of a Ty1 restriction factor reveals the molecular basis of transposition copy number control
Excessive replication of Saccharomyces cerevisiae Ty1 retrotransposons is regulated by
Copy Number Control, a process requiring the p22/p18 protein produced from a sub …
Copy Number Control, a process requiring the p22/p18 protein produced from a sub …
Viriforms—A New Category of Classifiable Virus-Derived Genetic Elements
The International Committee on Taxonomy of Viruses (ICTV) recently accepted viriforms as a
new polyphyletic category of classifiable virus-derived genetic elements, juxtaposed to the …
new polyphyletic category of classifiable virus-derived genetic elements, juxtaposed to the …
High-affinity anti-Arc nanobodies provide tools for structural and functional studies
Activity-regulated cytoskeleton-associated protein (Arc) is a multidomain protein of retroviral
origin with a vital role in the regulation of synaptic plasticity and memory formation in …
origin with a vital role in the regulation of synaptic plasticity and memory formation in …
Endogenous capsid-forming protein ARC for self-assembling nanoparticle vaccines
Y Li, X Zhao, J Tang, M Yi, X Zai, J Zhang… - Journal of …, 2024 - Springer
The application of nanoscale scaffolds has become a promising strategy in vaccine design,
with protein-based nanoparticles offering desirable avenues for the biocompatible and …
with protein-based nanoparticles offering desirable avenues for the biocompatible and …
[HTML][HTML] Structural properties and peptide ligand binding of the capsid homology domains of human Arc
The activity-regulated cytoskeleton-associated protein (Arc) is important for synaptic
plasticity and the normal function of the brain. Arc interacts with neuronal postsynaptic …
plasticity and the normal function of the brain. Arc interacts with neuronal postsynaptic …
[HTML][HTML] PNMA2 forms non-enveloped virus-like capsids that trigger paraneoplastic neurological syndrome
The paraneoplastic Ma antigen (PNMA) genes are associated with cancer-induced
paraneoplastic syndromes that present with neurological symptoms and autoantibody …
paraneoplastic syndromes that present with neurological symptoms and autoantibody …