Aortic valve stenosis: from basic mechanisms to novel therapeutic targets
Aortic valve stenosis is the most prevalent heart valve disease worldwide. Although
interventional treatment options have rapidly improved in recent years, symptomatic aortic …
interventional treatment options have rapidly improved in recent years, symptomatic aortic …
Bicuspid aortic valve: identifying knowledge gaps and rising to the challenge from the International Bicuspid Aortic Valve Consortium (BAVCon)
Given the high incidence of BAV dysfunction requiring surgical intervention and the high
incidence of associated TAA formation8–10, 14–18 (Table), the BAV condition should be …
incidence of associated TAA formation8–10, 14–18 (Table), the BAV condition should be …
Calcific aortic valve disease: a consensus summary from the Alliance of Investigators on Calcific Aortic Valve Disease
Calcific aortic valve disease (CAVD) is increasingly prevalent worldwide with significant
morbidity and mortality. Therapeutic options beyond surgical valve replacement are …
morbidity and mortality. Therapeutic options beyond surgical valve replacement are …
Is aortopathy in bicuspid aortic valve disease a congenital defect or a result of abnormal hemodynamics? A critical reappraisal of a one-sided argument
E Girdauskas, MA Borger, MA Secknus… - European Journal of …, 2011 - academic.oup.com
Although there is adequate evidence that bicuspid aortic valve (BAV) is an inheritable
disorder, there is a great controversy regarding the pathogenesis of dilatation of the proximal …
disorder, there is a great controversy regarding the pathogenesis of dilatation of the proximal …
Computational assessment of bicuspid aortic valve wall-shear stress: implications for calcific aortic valve disease
The bicuspid aortic valve (BAV) is associated with a high prevalence of calcific aortic valve
disease (CAVD). Although abnormal hemodynamics has been proposed as a potential …
disease (CAVD). Although abnormal hemodynamics has been proposed as a potential …
Characterization of abnormal wall shear stress using 4D flow MRI in human bicuspid aortopathy
There exists considerable controversy surrounding the timing and extent of aortic resection
for patients with BAV disease. Since abnormal wall shear stress (WSS) is potentially …
for patients with BAV disease. Since abnormal wall shear stress (WSS) is potentially …
Risk of late aortic events after an isolated aortic valve replacement for bicuspid aortic valve stenosis with concomitant ascending aortic dilation
E Girdauskas, K Disha, HH Raisin… - European journal of …, 2012 - academic.oup.com
OBJECTIVES The optimal surgical treatment of patients with bicuspid aortic valve (BAV)
disease and ascending aortic aneurysm is controversial. The aim of this study was to …
disease and ascending aortic aneurysm is controversial. The aim of this study was to …
Numerical methods for fluid–structure interaction models of aortic valves
G Marom - Archives of Computational Methods in Engineering, 2015 - Springer
In the recent years, fluid structure interaction (FSI) models of the aortic valve and root have
become increasingly common for two main reasons. The medical reason is that millions of …
become increasingly common for two main reasons. The medical reason is that millions of …
Genetic bases of bicuspid aortic valve: the contribution of traditional and high-throughput sequencing approaches on research and diagnosis
Bicuspid aortic valve (BAV) is a common (0.5–2.0% of general population) congenital heart
defect with increased prevalence of aortic dilatation and dissection. BAV has an autosomal …
defect with increased prevalence of aortic dilatation and dissection. BAV has an autosomal …
[HTML][HTML] Long-term prognosis of ascending aortic aneurysm after aortic valve replacement for bicuspid versus tricuspid aortic valve stenosis
E Girdauskas, K Disha, MA Borger, T Kuntze - The Journal of thoracic and …, 2014 - Elsevier
Objective The bicuspid aorta is thought to have a higher risk of progressive dilation after
aortic valve replacement with a subsequently increased risk of adverse aortic events. Our …
aortic valve replacement with a subsequently increased risk of adverse aortic events. Our …