5‑Fluorouracil and capecitabine therapies for the treatment of colorectal cancer
Although 5-fluorouracil (5-FU)-based chemotherapy is the major treatment for colorectal
cancer, it has disadvantages such as systemic toxicity, lack of effectiveness and selectivity …
cancer, it has disadvantages such as systemic toxicity, lack of effectiveness and selectivity …
Multifunctional microrobot with real-time visualization and magnetic resonance imaging for chemoembolization therapy of liver cancer
Microrobots that can be precisely guided to target lesions have been studied for in vivo
medical applications. However, existing microrobots have challenges in vivo such as …
medical applications. However, existing microrobots have challenges in vivo such as …
Cyclodextrin as a magic switch in covalent and non-covalent anticancer drug release systems
B Tian, Y Liu, J Liu - Carbohydrate polymers, 2020 - Elsevier
Cancer has been a threat to human health, so its treatment is a huge challenge to the
present medical field. One of commonly used methods is the controlled release of anticancer …
present medical field. One of commonly used methods is the controlled release of anticancer …
Cocrystallization of 5-fluorouracil with gallic acid: A novel 5-fluorouracil cocrystal displaying synergistic anti-tumor activity both in oral and intraperitoneal injection …
H Hao, Y Zhang, X Hu, W Guo, C Yang… - European Journal of …, 2023 - Elsevier
Gallic acid (GA) is a naturally occurring polyphenolic compound exhibiting anti-tumor
activity. To clarify the capability of GA in optimizing the in vitro/in vivo properties of the first …
activity. To clarify the capability of GA in optimizing the in vitro/in vivo properties of the first …
[HTML][HTML] Alginate/geopolymer hybrid beads as an innovative adsorbent applied to the removal of 5-fluorouracil from contaminated environmental water
Water contaminated by cytostatic drugs has many negative impacts on the ecosystems. In
this work, cross-linked adsorbent beads based on alginate and a geopolymer (prepared …
this work, cross-linked adsorbent beads based on alginate and a geopolymer (prepared …
Folic acid functionalized carbon nanotubes as pH controlled carriers of fluorouracil: Molecular dynamics simulations
M Yahyavi, F Badalkhani-Khamseh… - Journal of Molecular …, 2023 - Elsevier
This study deals with molecular dynamics simulations of the folic acid (FA) functionalized
carbon nanotube (CNT) as a pH-responsive carrier of fluorouracil (5-FU) drug. We chose FA …
carbon nanotube (CNT) as a pH-responsive carrier of fluorouracil (5-FU) drug. We chose FA …
Bovine Serum Albumin as a Platform for Designing Biologically Active Nanocarriers—Experimental and Computational Studies
O Adamczyk, M Szota, K Rakowski… - International Journal of …, 2023 - mdpi.com
Due to the specificity of their structure, protein systems are adapted to carry various ligands.
The structure of many proteins potentially allows for two types of immobilization of a …
The structure of many proteins potentially allows for two types of immobilization of a …
The effect of niosome preparation methods in encapsulating 5-fluorouracil and real time cell assay against HCT-116 colon cancer cell line
The formulation of niosomes is influenced by a number of variables, and these variables
may eventually affect the formulation's outcome. One of the elements that can influence the …
may eventually affect the formulation's outcome. One of the elements that can influence the …
Exploring pH dependent delivery of 5-fluorouracil from functionalized multi-walled carbon nanotubes
Multi-walled carbon nanotubes (MWCNTs) can be applied for pH-sensitive delivery of
anticancer drugs. Due to the importance of 5-fluorouracil (5-FU) in different tumor therapy …
anticancer drugs. Due to the importance of 5-fluorouracil (5-FU) in different tumor therapy …
pH-sensitive polyacrylic acid-gated mesoporous silica nanocarrier incorporated with calcium ions for controlled drug release
In this work, polyacrylic acid-functionalized MCM-41 was synthesized, which was made to
interact with calcium ions, in order to realize enhanced pH-responsive nanocarriers for …
interact with calcium ions, in order to realize enhanced pH-responsive nanocarriers for …