The early 2000s brought a new age in the field of mass spectrometry (MS) with the
introduction of ambient ionization MS techniques. As defined by one of its early visionaries …

Ambient ionization mass spectrometry (AIMS) has grown into a group of emerging analytical
techniques that allow rapid, real-time, high-throughput, in situ, and in vivo analysis in many …

Conventional methods for histopathologic tissue diagnosis are labor-and time-intensive and
can delay decision-making during diagnostic and therapeutic procedures. We report the …

Tissue diagnosis is important during surgical excision of solid tumors for margin evaluation.
Conventional histopathologic methods rely heavily on image-based visual diagnosis by …

Mass spectrometry is being used in many clinical research areas ranging from toxicology to
personalized medicine. Of all the mass spectrometry techniques, mass spectrometry …

Intraoperative delineation of tumor margins is critical for effective pancreatic cancer surgery.
Yet, intraoperative frozen section analysis of tumor margins is a time-consuming and often …

Molecular heterogeneity is a key feature of glioblastoma that impedes patient stratification
and leads to large discrepancies in mean patient survival. Here, we analyze a cohort of 96 …

Metabolomics is a nascent field of inquiry that emerged in the late 20 th century. It
encompasses the comprehensive profiling of metabolites across a spectrum of organisms …

Rapid and accurate clinical diagnosis remains challenging. A component of diagnosis tool
development is the design of effective classification models with Mass spectrometry (MS) …

BACKGROUND Accurate tissue diagnosis during ovarian cancer surgery is critical to
maximize cancer excision and define treatment options. Yet, current methods for …