Use of chimeric antigen receptor-modified T-cells to treat cancer

CH June, BL Levine, DL Porter, MD Kalos… - US Patent …, 2016 - Google Patents
The present invention provides compositions and methods for treating cancer in a human.
The invention includes relates to administering a genetically modified T cell to express a …

Methods for treatment of cancer

CH June, BL Levine, DL Porter, MD Kalos… - US Patent …, 2014 - Google Patents
US8906682B2 - Methods for treatment of cancer - Google Patents US8906682B2 - Methods for
treatment of cancer - Google Patents Methods for treatment of cancer Download PDF Info …

Nucleic acid encoding a humanized anti-BCMA chimeric antigen receptor

J Brogdon, E Choi, HE Ebersbach, D Glass… - US Patent …, 2019 - Google Patents
2017-05-31 Assigned to NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH, INC.
reassignment NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH, INC. ASSIGNMENT …

Compositions for treatment of cancer

CH June, BL Levine, DL Porter, MD Kalos… - US Patent …, 2014 - Google Patents
6,103,521 A 8/2000 Capon et al. 6,319,494 B1 11/2001 Capon et a1. 6,355,779 B1 3/2002
Goodwin et al. 6,410,319 B1 6/2002 Raubitschek et al. 6,569,997 B1 5/2003 Kwon …

Chimeric receptors with 4-1BB stimulatory signaling domain

D Campana, C Imai - US Patent 8,399,645, 2013 - Google Patents
The present invention relates to a chimeric receptor capable of signaling both a primary and
a co-stimulatory pathway, thus allowing activation of the co-stimulatory pathway with out …

Treatment of cancer using humanized anti-cd19 chimeric antigen receptor

J Brogdon, CH June, A Loew, M Maus… - US Patent …, 2019 - Google Patents
2016-03-07 Assigned to THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
reassignment THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA ASSIGNMENT …

Compositions for treatment of cancer

CH June, BL Levine, DL Porter, MD Kalos… - US Patent …, 2015 - Google Patents
The present invention provides compositions and methods for treating cancer in a human.
The invention includes relates to administering a genetically modified T cell to express a …

Methods for treatment of cancer

CH June, BL Levine, DL Porter, MD Kalos… - US Patent …, 2014 - Google Patents
US8916381B1 - Methods for treatment of cancer - Google Patents US8916381B1 - Methods
for treatment of cancer - Google Patents Methods for treatment of cancer Download PDF Info …

Method and compositions using a chimeric antigen receptor for enhanced anti-tumor effector functioning of T cells

M Jensen - US Patent 8,822,647, 2014 - Google Patents
Integration of costimulatory signaling domains within a tumor targeting chimeric antigen
receptor (CAR), such as the IL13Ro 2 specific IL 13-zetakine (IL13.), enhances T …

Methods for treatment of cancer

CH June, BL Levine, DL Porter, MD Kalos… - US Patent …, 2015 - Google Patents
US9101584B2 - Methods for treatment of cancer - Google Patents US9101584B2 - Methods for
treatment of cancer - Google Patents Methods for treatment of cancer Download PDF Info …