1, 2, 3‐Triazole hybrids as anticancer agents: A review
MM Alam - Archiv der Pharmazie, 2022 - Wiley Online Library
Despite the advancements in the development of anticancer agents, more effective and
safer anticancer drugs still need to be developed as the current agents cause unwanted side …
safer anticancer drugs still need to be developed as the current agents cause unwanted side …
Design, synthesis, molecular modeling, anticancer studies, and density functional theory calculations of 4-(1, 2, 4-triazol-3-ylsulfanylmethyl)-1, 2, 3-triazole derivatives
New conjugates of substituted 1, 2, 3-triazoles linked to 1, 2, 4-triazoles were synthesized
starting from the appropriate S-propargylated 1, 2, 4-triazoles 7 and 8. Ligation of 1, 2, 4 …
starting from the appropriate S-propargylated 1, 2, 4-triazoles 7 and 8. Ligation of 1, 2, 4 …
SBFI26 induces triple‐negative breast cancer cells ferroptosis via lipid peroxidation
G He, Y Zhang, Y Feng, T Chen, M Liu… - Journal of Cellular …, 2024 - Wiley Online Library
SBFI26, an inhibitor of FABP5, has been shown to suppress the proliferation and metastasis
of tumour cells. However, the underlying mechanism by which SBFI26 induces ferroptosis in …
of tumour cells. However, the underlying mechanism by which SBFI26 induces ferroptosis in …
Quinoline‐based thiazolidinone derivatives as potent cytotoxic and apoptosis‐inducing agents through EGFR inhibition
Quinoline‐based thiazolidinone heterocycles exhibited potent activity in the field of cancer
therapy. Hence, ten quinoline‐based thiazolidinone derivatives were evaluated for their …
therapy. Hence, ten quinoline‐based thiazolidinone derivatives were evaluated for their …
Recent progress on apoptotic activity of triazoles
P Çıkla-Süzgün, ŞG Küçükgüzel - Current drug targets, 2021 - ingentaconnect.com
Apoptosis is often called programmed cell death and is defined as a self-directed cell
destruction process. It is different from necrosis due to the activation of caspases during this …
destruction process. It is different from necrosis due to the activation of caspases during this …
Synthesis and antimalarial and anticancer evaluation of 7‐chlorquinoline‐4‐thiazoleacetic derivatives containing aryl hydrazide moieties
H Ramírez, E Fernandez, J Rodrigues… - Archiv der …, 2021 - Wiley Online Library
Twelve 7‐chloroquinoline derivatives were designed and synthesized using the principle of
molecular hybridization through the coupling of 2‐[2‐(7‐chloroquinolin‐4‐ylthio)‐4 …
molecular hybridization through the coupling of 2‐[2‐(7‐chloroquinolin‐4‐ylthio)‐4 …
Synthesis, characterization and cytotoxic activity evaluation of 4-(1, 2, 3-triazol-1-yl) salicylic acid derivatives
ZG Ríos-Malváez, MA Cano-Herrera… - Journal of Molecular …, 2021 - Elsevier
Abstract A novel series of 4-(1, 2, 3-triazol-1-yl) salicylic acid derivatives was synthesized
from 4-azidosalicylic acid and diverse alkynes using copper catalyzed azide-alkyne …
from 4-azidosalicylic acid and diverse alkynes using copper catalyzed azide-alkyne …
Hybridized 4‐Trifluoromethyl‐(1, 2, 3‐triazol‐1‐yl) quinoline System: Synthesis, Photophysics, Selective DNA/HSA Bio‐interactions and Molecular Docking
The synthesis, structural analysis, and evaluation of the photophysical properties of twelve
novel 2‐aryl (heteroaryl)‐6‐(4‐alkyl (aryl)‐1H‐1, 2, 3‐triazol‐1‐yl)‐4‐(trifluoromethyl) …
novel 2‐aryl (heteroaryl)‐6‐(4‐alkyl (aryl)‐1H‐1, 2, 3‐triazol‐1‐yl)‐4‐(trifluoromethyl) …
New 3‐(1H‐benzo[d]imidazol‐2‐yl)quinolin‐2(1H)‐one‐based triazole derivatives: Design, synthesis, and biological evaluation as antiproliferative and apoptosis …
Abstract A series of 1, 2, 3‐triazole derivatives based on the quinoline–benzimidazole hybrid
scaffold was designed, synthesized, and screened against a panel of NCI‐60 humanoid …
scaffold was designed, synthesized, and screened against a panel of NCI‐60 humanoid …
Synthesis of [1,2,3]Triazolo[1,5‐a]quinoline‐3‐carboxamides Promoted by Organocatalyst and Base
GP Da Costa, GB Blödorn, T Barcellos… - European Journal of …, 2023 - Wiley Online Library
We described here a simple and metal‐free protocol to synthesize [1, 2, 3] triazolo [1, 5‐a]
quinoline 3‐carboxamides through a two‐step synthetic strategy, in which the first step uses …
quinoline 3‐carboxamides through a two‐step synthetic strategy, in which the first step uses …