[HTML][HTML] Nanostructured lipid carriers (NLCs) as drug delivery platform: Advances in formulation and delivery strategies

M Elmowafy, MM Al-Sanea - Saudi Pharmaceutical Journal, 2021 - Elsevier
NLCs have provoked the incessant impulsion for the development of safe and valuable drug
delivery systems owing to their exceptional physicochemical and then biocompatible …

Nanostructured lipid carriers: Promising drug delivery systems for future clinics

A Beloqui, MÁ Solinís, A Rodríguez-Gascón… - … , biology and medicine, 2016 - Elsevier
During the past decade, the number of studies describing nanostructured lipid carriers
(NLCs)-based formulations has been dramatically increased. The raise in NLC exploitation …

Polyprodrug nanomedicines: an emerging paradigm for cancer therapy

K Yang, Z Yang, G Yu, Z Nie, R Wang… - Advanced …, 2022 - Wiley Online Library
Nanomedicines have the potential to provide advanced therapeutic strategies in combating
tumors. Polymer‐prodrug‐based nanomedicines are particularly attractive in cancer …

Optimization of nanostructured lipid carriers: Understanding the types, designs, and parameters in the process of formulations

B Subramaniam, ZH Siddik, NH Nagoor - Journal of nanoparticle research, 2020 - Springer
Lipid-based nanoparticles for drug delivery have been employed in the development of
nanomedicine for various applications. One such versatile nanoparticle type is …

[HTML][HTML] Time to conquer fungal infectious diseases: employing nanoparticles as powerful and versatile antifungal nanosystems against a wide variety of fungal …

A Jangjou, Z Zareshahrabadi, M Abbasi… - Sustainability, 2022 - mdpi.com
The development of novel antifungal agents and, in particular, the widespread use of these
medications over the course of the past two decades, has had a significant impact on the …

Chitosan coated nanostructured lipid carriers for brain delivery of proteins by intranasal administration

O Gartziandia, E Herran, JL Pedraz, E Carro… - Colloids and Surfaces B …, 2015 - Elsevier
The remarkable increase in the prevalence of neurodegenerative diseases has become a
serious public health problem. Considering the lack of effective treatments to address these …

A novel strategy for the treatment of chronic wounds based on the topical administration of rhEGF-loaded lipid nanoparticles: In vitro bioactivity and in vivo …

G Gainza, M Pastor, JJ Aguirre, S Villullas… - Journal of controlled …, 2014 - Elsevier
Lipid nanoparticles are currently receiving increasing interest because they permit the
topical administration of proteins, such as recombinant human epidermal growth factor …

Therapies and vaccines based on nanoparticles for the treatment of systemic fungal infections

B Kischkel, SA Rossi, SR Santos… - Frontiers in cellular …, 2020 - frontiersin.org
Treatment modalities for systemic mycoses are still limited. Currently, the main antifungal
therapeutics include polyenes, azoles, and echinocandins. However, even in the setting of …

Improved bioavailability of poorly soluble drugs through gastrointestinal muco-adhesion of lipid nanoparticles

SLJ Tan, N Billa - Pharmaceutics, 2021 - mdpi.com
Gastrointestinal absorption remains indispensable in the systemic delivery of most drugs,
even though it presents several challenges that, paradoxically, may also provide …

Nanostructured lipid carriers as oral delivery systems for poorly soluble drugs

A Beloqui, A del Pozo-Rodríguez, A Isla… - Journal of Drug Delivery …, 2017 - Elsevier
Poorly water soluble (PWS) drugs lack from good oral absorption, which limits their oral
administration, the most common drug delivery route. The design of appropriate innovative …