The understanding of complex inhalation and transport processes of pollutant particles
through the human respiratory system is important for investigations into dosimetry and …

Introduction: Respiratory drug delivery is a surprisingly complex process with a number of
physical and biological challenges. Computational fluid dynamics (CFD) is a scientific …

Prediction of the air-particle dynamics in human lungs can reveal critical deposition sites of
toxins or can determine best physical parameters for direct drug delivery and associated …

Effective evaluation and prediction of aerosol transport deposition in the human respiratory
tracts are critical to aerosol drug delivery and evaluation of inhalation products …

Dynamic modeling of how particulate matter (PM) transport, deposit, and translocate from
human respiratory systems to systemic regions subject to indoor and outdoor exposures are …

Dosimetry models for the estimation of particle deposition in the human respiratory tract (RT)
in conjunction with clearance transport models are vital components to relate human …

The United States has witnessed a concerning surge in the incidence of diseases like Coal
Workers' Pneumoconiosis (CWP), despite numerous efforts aimed at prevention. This study …

This article reviews recent developments in computational modeling of dry powder inhalers
(DPIs). DPIs deliver drug formulations (sometimes blended with larger carrier particles) to a …

The measurement of deposited aerosol particles in the respiratory tract via in vivo and in
vitro approaches is difficult due to those approaches' many limitations. In order to overcome …

Part of the effective prediction of the pharmacokinetics of drugs (or toxic particles) requires
extrapolation of experimental data sets from animal studies to humans. As the respiratory …