The pleiotropic biochemical and antioxidant functions of vitamin C have sparked recent
interest in its application in intensive care. Vitamin C protects important organ systems …

Background Prothrombin complex concentrate (PCC) has recently emerged as an effective
alternative to fresh frozen plasma (FFP) in treating excessive perioperative bleeding. This …

Coronary artery disease is one of the commonest surgery demanding cardiovascular
diseases. Coronary artery bypass graft surgery is practiced all over the world for the …

Introduction: Intraoperative surgical sealants and hemostatic agents have been shown to
reduce postoperative complications, transfusions, and hospital resource utilization. Despite …

BACKGROUND: Declining platelet counts may reveal platelet activation and aggregation in
a postoperative prothrombotic state. Therefore, we hypothesized that nadir platelet counts …

Background Patients with perioperative bleeding during cardiac surgery are susceptible to
acute kidney injury (AKI) which is proposed to be associated with short-term and long-term …

Background: Blood transfusion (BT) can be mandated during cardiopulmonary bypass
(CPB)-aided surgery, although it poses a risk for morbidity and mortality. However …

Materials and Methods: In a randomized, blinded, prospective trial of patients undergoing
elective, complex cardiac surgery with cardiopulmonary bypass, patients were randomized …

Objective: Minimal invasive extracorporeal circulation may decrease the need of packed red
blood cell transfusions and reduce hemodilution during cardiopulmonary bypass. However …

Purpose To evaluate the impact of transfusion on the development of stroke after
cardiovascular interventions. Methods A literature search was performed to identify …