The roles and implications of RNA m6A modification in cancer

X Deng, Y Qing, D Horne, H Huang… - Nature Reviews Clinical …, 2023 - nature.com
Abstract N 6-Methyladenosine (m6A), the most prevalent internal modification in eukaryotic
mRNA, has been extensively and increasingly studied over the past decade. Dysregulation …

[HTML][HTML] CLIP and complementary methods

M Hafner, M Katsantoni, T Köster, J Marks… - Nature Reviews …, 2021 - nature.com
RNA molecules start assembling into ribonucleoprotein (RNP) complexes during
transcription. Dynamic RNP assembly, largely directed by cis-acting elements on the RNA …

Genetically encoded chemical crosslinking of RNA in vivo

W Sun, N Wang, H Liu, B Yu, L **, X Ren, Y Shen… - Nature …, 2023 - nature.com
Protein–RNA interactions regulate RNA fate and function, and defects can lead to various
disorders. Such interactions have mainly been studied by nucleoside-based UV crosslinking …

Deepm5C: a deep-learning-based hybrid framework for identifying human RNA N5-methylcytosine sites using a stacking strategy

MM Hasan, S Tsukiyama, JY Cho, H Kurata, MA Alam… - Molecular Therapy, 2022 - cell.com
As one of the most prevalent post-transcriptional epigenetic modifications, N5-
methylcytosine (m5C) plays an essential role in various cellular processes and disease …