Recognizing the importance of childhood maltreatment as a critical factor in psychiatric diagnoses, treatment, research, prevention, and education

MH Teicher, JB Gordon, CB Nemeroff - Molecular psychiatry, 2022 - nature.com
Childhood maltreatment is the most important preventable risk factor for psychiatric
disorders. Maltreated individuals typically develop psychiatric disorders at an earlier age …

Early life stress and development: potential mechanisms for adverse outcomes

KE Smith, SD Pollak - Journal of neurodevelopmental disorders, 2020 - Springer
Background Chronic and/or extreme stress in early life, often referred to as early adversity,
childhood trauma, or early life stress, has been associated with a wide range of adverse …

Stress and adolescence: vulnerability and opportunity during a sensitive window of development

LM Sisk, DG Gee - Current Opinion in Psychology, 2022 - Elsevier
Adolescence is a period of dynamic change across multiple systems. Concurrent maturation
of neural, biological, and psychosocial functioning renders adolescence a time of …

[HTML][HTML] Social vulnerabilities for substance use: Stressors, socially toxic environments, and discrimination and racism

H Amaro, M Sanchez, T Bautista, R Cox - Neuropharmacology, 2021 - Elsevier
Applying a social determinants of health framework, this review brings attention to evidence
from social sciences and neuroscience on the role of selected social factors in individual …

Rethinking concepts and categories for understanding the neurodevelopmental effects of childhood adversity

KE Smith, SD Pollak - Perspectives on psychological science, 2021 - journals.sagepub.com
Discovering the processes through which early adverse experiences affect children's
nervous-system development, health, and behavior is critically important for develo** …

Adverse childhood experiences and the consequences on neurobiological, psychosocial, and somatic conditions across the lifespan

JI Herzog, C Schmahl - Frontiers in psychiatry, 2018 - frontiersin.org
Introduction: Adverse childhood experiences (ACE) such as sexual and physical abuse or
neglect are frequent in childhood and constitute a massive stressor with long-lasting …

The effect of multiple adverse childhood experiences on health: a systematic review and meta-analysis

K Hughes, MA Bellis, KA Hardcastle, D Sethi… - The Lancet public …, 2017 - thelancet.com
Background A growing body of research identifies the harmful effects that adverse childhood
experiences (ACEs; occurring during childhood or adolescence; eg, child maltreatment or …

Why is depression more common among women than among men?

C Kuehner - The lancet psychiatry, 2017 - thelancet.com
Women are about twice as likely as are men to develop depression during their lifetime. This
Series paper summarises evidence regarding the epidemiology on gender differences in …

The effects of childhood maltreatment on brain structure, function and connectivity

MH Teicher, JA Samson, CM Anderson… - Nature reviews …, 2016 - nature.com
Maltreatment-related childhood adversity is the leading preventable risk factor for mental
illness and substance abuse. Although the association between maltreatment and …