Quality by Design (QbD) application for the pharmaceutical development process
SH Lee, JK Kim, JP Jee, DJ Jang, YJ Park… - Journal of …, 2022 - Springer
Abstract Background Quality by Design (QbD) is a pharmaceutical quality management
system that predicts, controls, and systematically responds to risks that may occur in the …
system that predicts, controls, and systematically responds to risks that may occur in the …
[HTML][HTML] A mini-review on drug delivery through wafer technology: Formulation and manufacturing of buccal and oral lyophilizates
A great number of patients have difficulty swallowing or needle fear. Therefore, buccal and
orodispersible dosage forms (ODFs) represent an important strategy to enhance patient …
orodispersible dosage forms (ODFs) represent an important strategy to enhance patient …
Orally dispersible dosage forms for paediatric use: current knowledge and development of nanostructure-based formulations
The paediatric population has always suffered from a lack of medicines tailored to their
needs, especially in terms of accurate dosage, stability and acceptability. Orodispersible …
needs, especially in terms of accurate dosage, stability and acceptability. Orodispersible …
A Design of Experiments Strategy to Enhance the Recovery of Polyphenolic Compounds from Vitis vinifera By-Products through Heat Reflux Extraction
The aim of the present study was to establish the best experimental conditions that lead to
the extracts richest in polyphenolic compounds obtained from pomace and canes of Vitis …
the extracts richest in polyphenolic compounds obtained from pomace and canes of Vitis …
Critical tools in tableting research: Using compaction simulator and quality by design (QbD) to evaluate lubricants' effect in direct compressible formulation
As commonly known, the product development stage is quite complex, requires intensive
knowledge, and is time-consuming. The selection of the excipients with the proper …
knowledge, and is time-consuming. The selection of the excipients with the proper …
Application of Quality by Design Principles to the Development of Oral Lyophilizates Containing Olanzapine
M Bjelošević Žiberna, P Ahlin Grabnar - Pharmaceutics, 2023 - mdpi.com
Oral lyophilizates are intended for application to the oral cavity or for dispersing in water.
The purposes of this research were:(i) to set up the quality by design approach in the …
The purposes of this research were:(i) to set up the quality by design approach in the …
[PDF][PDF] DESIGN OF EXPERIMENTS APPROACH TO ASSESS THE IMPACT OF API PARTICLE SIZE ON FREEZE-DRIED BULKING AGENTS.
The current work aimed at the thorough characterization of freeze-dried bulking agent
structures loaded with different particle sizes of active pharmaceutical ingredient (API) …
structures loaded with different particle sizes of active pharmaceutical ingredient (API) …
[PDF][PDF] Formulation of orodispersible tablets containing paracetamol and their in vitro characterization-a QbD approach
Abstract Quality by Design (QbD) concept in drug formulation and development was
introduced in order to achieve and ensure a proper product quality through a good process …
introduced in order to achieve and ensure a proper product quality through a good process …
[HTML][HTML] Development of a Mouthwash Using Freeze-Drying Technique: An Optimization Study
In recent years, the development of solid cosmetics, as part of sustainable cosmetics
strategy, is generating increasing interest. In addition, novel approaches such as Quality by …
strategy, is generating increasing interest. In addition, novel approaches such as Quality by …
Preparation and in vitro–in vivo evaluation of QbD based acemetacin loaded transdermal patch formulations for rheumatic diseases
This research aimed to develop patches for transdermal delivery of acemetacin, which can
be used to treat rheumatic diseasesand to determine their potential use. Patches were …
be used to treat rheumatic diseasesand to determine their potential use. Patches were …