Hepatocytes: A key role in liver inflammation

J Gong, W Tu, J Liu, D Tian - Frontiers in immunology, 2023 - frontiersin.org
Hepatocytes, the major parenchymal cells in the liver, are responsible for a variety of cellular
functions including carbohydrate, lipid and protein metabolism, detoxification and immune …

[HTML][HTML] Saliva as a potential non-invasive liquid biopsy for early and easy diagnosis/prognosis of head and neck cancer

P Kumar, S Gupta, BC Das - Translational oncology, 2024 - Elsevier
Head and neck squamous cell carcinomas (HNSCCs) are the most devastating diseases in
India and southeast Asia. It is a preventable and curable disease if detected early. Tobacco …

AdMSC-derived exosomes alleviate acute lung injury via transferring mitochondrial component to improve homeostasis of alveolar macrophages

L **a, C Zhang, N Lv, Z Liang, T Ma, H Cheng… - …, 2022 - pmc.ncbi.nlm.nih.gov
Rationale: Aberrant activation of macrophages with mitochondria dismiss was proved to be
associated with pathogenesis of ALI (acute lung injury). Exosomes from adipose-derived …

Extracellular vesicles: mediators of intercellular communication in tissue injury and disease

G Berumen Sánchez, KE Bunn, HH Pua… - Cell Communication and …, 2021 - Springer
Intercellular communication is a critical process that ensures cooperation between distinct
cell types and maintains homeostasis. EVs, which were initially described as cellular debris …

[HTML][HTML] Extracellular vesicles in nanomedicine and regenerative medicine: a review over the last decade

S Moghassemi, A Dadashzadeh, MJ Sousa, H Vlieghe… - Bioactive materials, 2024 - Elsevier
Small extracellular vesicles (sEVs) are known to be secreted by a vast majority of cells.
These sEVs, specifically exosomes, induce specific cell-to-cell interactions and can activate …

RNA in extracellular vesicles

KM Kim, K Abdelmohsen, M Mustapic… - Wiley …, 2017 - Wiley Online Library
Cells release a range of membrane‐enclosed extracellular vesicles (EVs) into the
environment. Among them, exosomes and microvesicles (collectively measuring 40–1000 …

Tumorigenesis, diagnosis, and therapeutic potential of exosomes in liver cancer

H Wang, Z Lu, X Zhao - Journal of hematology & oncology, 2019 - Springer
Hepatocellular carcinoma (HCC, also called primary liver cancer) is one of the most fatal
cancers in the world. Due to the insidiousness of the onset of HCC and the lack of effective …

Immunological mechanisms and therapeutic targets of fatty liver diseases

H Wang, W Mehal, LE Nagy, Y Rotman - Cellular & Molecular …, 2021 - nature.com
Alcoholic liver disease (ALD) and nonalcoholic fatty liver disease (NAFLD) are the two major
types of chronic liver disease worldwide. Inflammatory processes play key roles in the …

[HTML][HTML] Alcohol-related liver disease: basic mechanisms and clinical perspectives

SY Liu, IT Tsai, YC Hsu - International journal of molecular sciences, 2021 - mdpi.com
Alcohol-related liver disease (ALD) refers to the liver damage occurring due to excessive
alcohol consumption and involves a broad spectrum of diseases that includes liver steatosis …

Peripheral circulating exosome-mediated delivery of miR-155 as a novel mechanism for acute lung inflammation

K Jiang, J Yang, S Guo, G Zhao, H Wu, G Deng - Molecular Therapy, 2019 - cell.com
Emerging evidence has revealed that excessive activation of macrophages may result in an
adverse lung inflammation involved in sepsis-related acute lung injury (ALI). However, it has …