Antimicrobial activity of quercetin: an approach to its mechanistic principle

TLA Nguyen, D Bhattacharya - Molecules, 2022 - mdpi.com
Quercetin, an essential plant flavonoid, possesses a variety of pharmacological activities.
Extensive literature investigates its antimicrobial activity and possible mechanism of action …

Anti-fungal efficacy and mechanisms of flavonoids

MS Al Aboody, S Mickymaray - Antibiotics, 2020 - mdpi.com
The prevalence of fungal infections is growing at an alarming pace and the pathogenesis is
still not clearly understood. Recurrence of these fungal diseases is often due to their …

Major challenges and perspectives in the diagnostics and treatment of dermatophyte infections

S Gnat, D Łagowski… - Journal of applied …, 2020 - academic.oup.com
Dermatophytes are the aetiological factors of a majority of superficial fungal infections. What
distinguishes them from other pathogenic filamentous fungi is their unique ability to degrade …

Chalcone scaffolds as anti-infective agents: Structural and molecular target perspectives

DK Mahapatra, SK Bharti, V Asati - European journal of medicinal chemistry, 2015 - Elsevier
In recent years, widespread outbreak of numerous infectious diseases across the globe has
created havoc among the population. Particularly, the inhabitants of tropical and sub-tropical …

Dermatophyte resistance to antifungal drugs: mechanisms and prospectus

NM Martinez-Rossi, TA Bitencourt, NTA Peres… - Frontiers in …, 2018 - frontiersin.org
Dermatophytes comprise pathogenic fungi that have a high affinity for the keratinized
structures present in nails, skin, and hair, causing superficial infections known as …

Epidemiology and diagnostic perspectives of dermatophytoses

MF Petrucelli, MH Abreu, BAM Cantelli, GG Segura… - Journal of Fungi, 2020 - mdpi.com
Dermatophytoses affect about 25% of the world population, and the filamentous fungus
Trichophyton rubrum is the main causative agent of this group of diseases. Dermatomycoses …

Antifungal Activity of Phenolic and Polyphenolic Compounds from Different Matrices of Vitis vinifera L. against Human Pathogens

G Simonetti, E Brasili, G Pasqua - Molecules, 2020 - mdpi.com
Phenolic compounds, the most widely distributed class of natural products in the plants,
show several biological properties including antifungal activity. Phenolics contained in …

Recent advances in natural antifungal flavonoids and their derivatives

YS ** - Bioorganic & medicinal chemistry letters, 2019 - Elsevier
The resistance of pathogenic fungi and failure of drug therapy increased dramatically.
Numerous studies have reported the individual or synergistic antifungal potency of natural …

Reprogramming of lipid metabolism in lung cancer: An overview with focus on EGFR-Mutated non-small cell lung cancer

K Eltayeb, S La Monica, M Tiseo, R Alfieri, C Fumarola - Cells, 2022 - mdpi.com
Lung cancer is the leading cause of cancer deaths worldwide. Most of lung cancer cases are
classified as non-small cell lung cancers (NSCLC). EGFR has become an important …

Quercetin ameliorates Aspergillus fumigatus keratitis by inhibiting fungal growth, toll-like receptors and inflammatory cytokines

J Yin, X Peng, J Lin, Y Zhang, J Zhang, H Gao… - International …, 2021 - Elsevier
Purpose To investigate the antifungal and anti-inflammatory effects of quercetin on
Aspergillus fumigatus (A. fumigatus) keratitis. Methods Human corneal epithelial cells …