Resolution of inflammation and the return of tissues to homeostasis are essential. Efforts to
identify molecular events governing termination of self-limited inflammation uncovered …

Glucocorticoids are widely used for the management of inflammatory diseases. Their clinical
application stems from our understanding of the inhibitory effect of the corticosteroid …

Endogenous mechanisms that act in the resolution of acute inflammation are essential for
host defense and the return to homeostasis. Resolvin D1 (RvD1), biosynthesized during …

Pyrazolone is a well-known influential synthon for the synthesis of many molecules which
hold remarkable potential in the advancement of functional materials, coordination …

The formyl peptide receptors (FPRs) are G protein-coupled receptors that transduce
chemotactic signals in phagocytes and mediate host-defense as well as inflammatory …

The formylpeptide receptors (FPRs) mediate pattern recognition of formylated peptides
derived from invading pathogens or mitochondria from dead host cells. They can also sense …

The popular view that all lipid mediators are pro-inflammatory arises largely from the finding
that nonsteroidal anti-inflammatory drugs block the biosynthesis of prostaglandins. The …

Current medicines for the clinical management of inflammatory diseases act by inhibiting
specific enzymes or antagonising specific receptors or blocking their ligands. In the past …

Chronic diseases that affect our society are made more complex by comorbidities and are
poorly managed by the current pharmacology. While all present inflammatory …

The formyl peptide receptor 1 (FPR1) is primarily responsible for detection of short peptides
bearing N-formylated methionine (fMet) that are characteristic of protein synthesis in bacteria …