Reframing chronic pain as a disease, not a symptom: rationale and implications for pain management

DJ Clauw, MN Essex, V Pitman… - Postgraduate medicine, 2019 - Taylor & Francis
Chronic pain is a common public health problem that has a detrimental impact on patient
health, quality of life (QoL), and function, and poses a substantial socioeconomic burden …

Objective measurements of sleep for non‐laboratory settings as alternatives to polysomnography–a systematic review

ATM Van de Water, A Holmes… - Journal of sleep …, 2011 - Wiley Online Library
Sleep disturbance influences human health. To examine sleep patterns, it is advisable to
utilize valid subjective and objective measures. Laboratory‐based polysomnography (PSG) …

Epidemiology of chronic low back pain in US adults: data from the 2009–2010 National Health and Nutrition Examination Survey

A Shmagel, R Foley, H Ibrahim - Arthritis care & research, 2016 - Wiley Online Library
Objective To describe the epidemiologic characteristics and associations with increased
health care utilization in US adults with chronic low back pain (LBP). Methods The National …

Long-term consequences of chronic pain: mounting evidence for pain as a neurological disease and parallels with other chronic disease states

PG Fine - Pain medicine, 2011 - academic.oup.com
Objective. This article reviews the potential physical and psychological consequences of
chronic pain and the importance of implementing effective therapeutic strategies to mitigate …

[HTML][HTML] Melatonin modulates IL-1β-induced extracellular matrix remodeling in human nucleus pulposus cells and attenuates rat intervertebral disc degeneration and …

Y Zhang, F He, Z Chen, Q Su, M Yan, Q Zhang… - Aging (albany …, 2019 - ncbi.nlm.nih.gov
The inflammatory-associated factors interleukin-1β (IL-1β), interleukin-6 (IL-6) and tumor
necrosis factor-α (TNF-α) are widely reported to be associated with intervertebral disc (IVD) …

One night of total sleep deprivation promotes a state of generalized hyperalgesia: a surrogate pain model to study the relationship of insomnia and pain

S Schuh-Hofer, R Wodarski, DB Pfau, O Caspani… - Pain®, 2013 - Elsevier
Sleep disturbances are highly prevalent in chronic pain patients. Understanding their
relationship has become an important research topic since poor sleep and pain are …

The association between chronic low back pain and sleep: a systematic review

GA Kelly, C Blake, CK Power, D O'keeffe… - The Clinical journal of …, 2011 - journals.lww.com
Objectives Chronic low back pain (CLBP) adversely affects many quality of life components,
and is reported to impair sleep. The aim of this review was to determine the association …

Prevalence of sleep disturbance in patients with low back pain

SM Alsaadi, JH McAuley, JM Hush, CG Maher - European Spine Journal, 2011 - Springer
Low back pain (LBP) is a common health condition that is often associated with disability,
psychological distress and work loss. Worldwide, billions of dollars are expended each year …

Patient insight into the impact of chronic obstructive pulmonary disease in the morning: an internet survey

MR Partridge, N Karlsson, IR Small - Current medical research and …, 2009 - Taylor & Francis
Objective: To determine diurnal variability of symptoms in chronic obstructive pulmonary
disease (COPD) and to assess the impact of COPD upon patients' morning activities and …

Prevalence of sleep deprivation in patients with chronic neck and back pain: a retrospective evaluation of 1016 patients

J Artner, B Cakir, JA Spiekermann, S Kurz… - Journal of pain …, 2012 - Taylor & Francis
Background Chronic low back pain (CLBP) and chronic neck pain (CNP) have become a
serious medical and socioeconomic problem in recent decades. Patients suffering from …