[HTML][HTML] Host genetic factors affecting hepatitis B infection outcomes: Insights from genome-wide association studies

IM Akcay, S Katrinli, K Ozdil, GD Doganay… - World journal of …, 2018 - ncbi.nlm.nih.gov
The clinical outcome of hepatitis B virus (HBV) infection depends on the success or failure of
the immune responses to HBV, and varies widely among individuals, ranging from …

Pattern recognition receptors: significance of expression in the liver

J Żeromski, A Kierepa, B Brzezicha… - Archivum Immunologiae …, 2020 - Springer
Pattern recognition receptors (PRRs) are a pivotal part of the immune system. They are
distributed in almost every site of higher organisms, able to recognize foreign pathogens or …

Association of toll-like receptors single nucleotide polymorphisms with HBV and HCV infection: research status

Y Xu, W Xue, H Gao, J Cui, L Zhao, C You - PeerJ, 2022 - peerj.com
Background Hepatitis B virus (HBV) and hepatitis C virus (HCV) infections have become
increasingly severe worldwide and are a threat to public health. There have been a number …

Advanced therapeutics, vaccinations, and precision medicine in the treatment and management of chronic hepatitis b viral infections; where are we and where are we …

GS Duraisamy, D Bhosale, I Lipenská, I Huvarova… - Viruses, 2020 - mdpi.com
The management of chronic hepatitis B virus (CHB) infection is an area of massive unmet
clinical need worldwide. In spite of the development of powerful nucleoside/nucleotide …

Recent advances in different interactions between toll-like receptors and hepatitis B infection: a review

S Soleiman-Meigooni, A Yarahmadi… - Frontiers in …, 2024 - frontiersin.org
Hepatitis B virus (HBV) B infections remain a primary global health concern. The
immunopathology of the infection, specifically the interactions between HBV and the host …

Genetic variation of TLR3 gene is associated with the outcome of hepatitis b infection in mauritanian patients: case control study

T Soumbara, C Bonnet, CT Hamed, F Veten… - BMC Infectious …, 2024 - Springer
Abstract Background Toll-Like receptors (TLRs) play an important role in the immune
response during hepatitis B virus (HBV) infection. In this study, we evaluated the association …

Toll-like receptor 9 polymorphisms and Hepatitis B virus clearance in Moroccan chronic carriers

H Chihab, I Zaidane, A Elhabazi, FZ Jadid, R El Fihri… - Gene, 2019 - Elsevier
Objectives Toll-like receptor 9 (TLR9) plays a crucial role in the innate immune response
against viral infections. The failure of this system may result, in an attenuated immune …

Association between TLR2, TLR4, and TLR5 genetic variants and the risk of hepatocellular carcinoma in Moroccan population

C Zerrad, M Lkhider, A Belkouchi… - … Nucleotides & Nucleic …, 2023 - Taylor & Francis
Hepatocellular carcinoma (HCC) is the fifth most common human malignancy and the fourth
most frequent cause of cancer-related deaths worldwide. Toll-like receptors (TLRs), are …

Genotype frequency of the common TLR4 SNPs in a Kurdish population: global reviews and out-of-African migrations

SS Niranji, SMA Al-Jaf - Human Biology, 2022 - muse.jhu.edu
Toll-like receptors (TLRs) are cellular innate immune receptors that explore microbial
molecules. For instance, TLR4 can sense bacterial lipopolysaccharides, inducing cytokines …

[HTML][HTML] Однонуклеотидные полиморфизмы членов суперсемейства интерлейкина-1: ассоциация с вирусными гепатитами В и С

НВ Власенко, НС Чурилова, ЯВ Панасюк… - Журнал …, 2021 - cyberleninka.ru
В обзоре представлена информация об однонуклеотидных полиморфизмах (single
nucleotide polymorphism, SNP) в генах некоторых интерлейкинов (IL), входящих в …