Microfluidic tissue engineering and bio‐actuation

M Filippi, T Buchner, O Yasa, S Weirich… - Advanced …, 2022 - Wiley Online Library
Bio‐hybrid technologies aim to replicate the unique capabilities of biological systems that
could surpass advanced artificial technologies. Soft bio‐hybrid robots consist of synthetic …

Surface modification for PDMS‐based microfluidic devices

J Zhou, DA Khodakov, AV Ellis, NH Voelcker - Electrophoresis, 2012 - Wiley Online Library
This review focuses on advances reported from April 2009 to May 2011 in PDMS surface
modifications for the application in microfluidic devices. PDMS surface modification …

Micro total analysis systems for cell biology and biochemical assays

ML Kovarik, PC Gach, DM Ornoff, Y Wang… - Analytical …, 2012 - ACS Publications
Novel applications of micro total analysis systems (μTAS) are addressing fundamental
biological questions, creating new biomedical reagents, and develo** innovative cell and …

Controlled electromechanical cell stimulation on-a-chip

A Pavesi, G Adriani, M Rasponi, IK Zervantonakis… - Scientific reports, 2015 - nature.com
Stem cell research has yielded promising advances in regenerative medicine, but standard
assays generally lack the ability to combine different cell stimulations with rapid sample …

A microfluidic device for whole-animal drug screening using electrophysiological measures in the nematode C. elegans

SR Lockery, SE Hulme, WM Roberts, KJ Robinson… - Lab on a Chip, 2012 - pubs.rsc.org
This paper describes the fabrication and use of a microfluidic device for performing whole-
animal chemical screens using non-invasive electrophysiological readouts of …

Controlling differentiation of stem cells for develo** personalized organ‐on‐chip platforms

A Geraili, P Jafari, MS Hassani… - Advanced …, 2018 - Wiley Online Library
Abstract Organ‐on‐chip (OOC) platforms have attracted attentions of pharmaceutical
companies as powerful tools for screening of existing drugs and development of new drug …

Simultaneous or sequential orthogonal gradient formation in a 3D cell culture microfluidic platform

SGM Uzel, OC Amadi, TM Pearl, RT Lee, PTC So… - Small, 2016 - Wiley Online Library
Biochemical gradients are ubiquitous in biology. At the tissue level, they dictate
differentiation patterning or cell migration. Recapitulating in vitro the complexity of such …

Engineering a 3D microfluidic culture platform for tumor-treating field application

A Pavesi, G Adriani, A Tay, ME Warkiani, WH Yeap… - Scientific reports, 2016 - nature.com
The limitations of current cancer therapies highlight the urgent need for a more effective
therapeutic strategy. One promising approach uses an alternating electric field; however, the …

[HTML][HTML] A microscale biomimetic platform for generation and electro-mechanical stimulation of 3D cardiac microtissues

R Visone, G Talò, P Occhetta, D Cruz-Moreira… - APL …, 2018 - pubs.aip.org
Organs-on-chip technology has recently emerged as a promising tool to generate advanced
cardiac tissue in vitro models, by recapitulating key physiological cues of the native …

Development of a redox-polymer-based electrochemical glucose biosensor suitable for integration in microfluidic 3D cell culture systems

L Navarro-Nateras, J Diaz-Gonzalez, D Aguas-Chantes… - Biosensors, 2023 - mdpi.com
The inclusion of online, in situ biosensors in microfluidic cell cultures is important to monitor
and characterize a physiologically mimicking environment. This work presents the …