Primary progressive aphasia: six questions in search of an answer
Here, we review recent progress in the diagnosis and management of primary progressive
aphasia—the language-led dementias. We pose six key unanswered questions that …
aphasia—the language-led dementias. We pose six key unanswered questions that …
Heterogeneity and overlap in the continuum of linguistic profile of logopenic and semantic variants of primary progressive aphasia: a Profile Analysis based on …
Background Primary progressive aphasia (PPA) diagnostic criteria underestimate the
complex presentation of semantic (sv) and logopenic (lv) variants, in which symptoms …
complex presentation of semantic (sv) and logopenic (lv) variants, in which symptoms …
Plasma neurofilament light chain predicts Alzheimer's disease in patients with subjective cognitive decline and mild cognitive impairment: A cross‐sectional and …
Background and purpose We aimed to evaluate the accuracy of plasma neurofilament light
chain (NfL) in predicting Alzheimer's disease (AD) and the progression of cognitive decline …
chain (NfL) in predicting Alzheimer's disease (AD) and the progression of cognitive decline …
Comparing two picture naming tasks in primary progressive aphasia: Insights from behavioural and neural results
Picture naming tests are widely used to evaluate language impairments in
neurodegenerative diseases, especially in Primary Progressive Aphasia (PPA). The …
neurodegenerative diseases, especially in Primary Progressive Aphasia (PPA). The …
Loss of speech and functional impairment in Alzheimer's disease-related primary progressive aphasia: predictive factors of decline
We aimed to identify features associated with different disease trajectories in Alzheimer's
disease (AD)-related primary progressive aphasia (PPA). We considered 23 patients …
disease (AD)-related primary progressive aphasia (PPA). We considered 23 patients …
Primary progressive aphasia in Italian and English: a cross-linguistic cohort study
Background and Objectives Current formulations of primary progressive aphasia (PPA)
derive largely from English-speaking patients. We hypothesized that language-specific …
derive largely from English-speaking patients. We hypothesized that language-specific …
Comprehensive qualitative characterization of linguistic performance profiles in primary progressive aphasia: a multivariate study with FDG-PET
Primary progressive aphasia (PPA) classification relies on profile characterization of
quantitatively impaired/spared performance in language tasks. In this study, we coextracted …
quantitatively impaired/spared performance in language tasks. In this study, we coextracted …
Matching clinical diagnosis and amyloid biomarkers in alzheimer's disease and frontotemporal dementia
Background: The aims of this study were to compare the diagnostic accuracy, sensitivity,
specificity, and positive and negative predictive values (PPV, NPV) of different cerebrospinal …
specificity, and positive and negative predictive values (PPV, NPV) of different cerebrospinal …
[HTML][HTML] Data-driven subtypes of mixed semantic-logopenic primary progressive aphasia: Linguistic features, biomarker profiles and brain metabolic patterns
Mixed primary progressive aphasia (mPPA) accounts for a substantial proportion of primary
progressive aphasia (PPA) cases. However, the lack of a standardised definition of this …
progressive aphasia (PPA) cases. However, the lack of a standardised definition of this …
[HTML][HTML] Case Study 2: A 60-Year-Old Man With Progressive Deficits in Language Output
K Thurin, V Patel, DL Perez… - The Journal of …, 2022 - Am Neuropsych Assoc
A 60-year-old right-handed man, who was a retired electrical engineer, presented to our
clinic after 2 years of insidious-onset progressive word-finding difficulties, as well as an …
clinic after 2 years of insidious-onset progressive word-finding difficulties, as well as an …