Ischemic stroke is one of the major health problems worldwide. The only FDA approved anti-
thrombotic drug for acute ischemic stroke is the tissue plasminogen activator. Several …

The ability of pluripotent stem cells to self-renew and differentiate into all somatic cell types
brings great prospects to regenerative medicine and human health. However, before clinical …

The mammary gland undergoes significant remodeling during pregnancy and lactation,
which is fuelled by controlled mammary stem cell (MaSC) proliferation. The scarcity of …

Cancer cells and embryonic tissues share a number of cellular and molecular properties,
suggesting that induced pluripotent stem cells (iPSCs) may be harnessed to elicit anti-tumor …

Neural stem cells (NSCs) hold great promise for neural repair in cases of CNS injury and
neurodegeneration; however, conventional cell-based transplant methods face the …

Over the course of the aging process, fibroblasts lose contractility, leading to reduced
connective-tissue stiffness. A promising therapeutic avenue for functional rejuvenation of …

The use of induced Pluripotent Stem Cells (iPSC) as a source of autologous tissues shows
great promise in regenerative medicine. Nevertheless, several major challenges remain to …

Advances in understanding how cancer cells interact with the immune system allowed the
development of immunotherapeutic strategies, harnessing patients' immune system to fight …

Epithelial stem cells (EpSCs) in the hair follicle bulge are required for hair follicle growth and
cycling. The isolation and propagation of human EpSCs for tissue engineering purposes …

Transplantation of human neural progenitor cells (NPCs) into the brain or spinal cord to
replace lost cells, modulate the injury environment, or create a permissive milieu to protect …