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The chemistry of plant–microbe interactions in the rhizosphere and the potential for metabolomics to reveal signaling related to defense priming and induced systemic …
Plant roots communicate with microbes in a sophisticated manner through chemical
communication within the rhizosphere, thereby leading to biofilm formation of beneficial …
communication within the rhizosphere, thereby leading to biofilm formation of beneficial …
Big data analytics in healthcare
The rapidly expanding field of big data analytics has started to play a pivotal role in the
evolution of healthcare practices and research. It has provided tools to accumulate, manage …
evolution of healthcare practices and research. It has provided tools to accumulate, manage …
Creation and analysis of biochemical constraint-based models using the COBRA Toolbox v. 3.0
Constraint-based reconstruction and analysis (COBRA) provides a molecular mechanistic
framework for integrative analysis of experimental molecular systems biology data and …
framework for integrative analysis of experimental molecular systems biology data and …
A community-driven global reconstruction of human metabolism
Multiple models of human metabolism have been reconstructed, but each represents only a
subset of our knowledge. Here we describe Recon 2, a community-driven, consensus' …
subset of our knowledge. Here we describe Recon 2, a community-driven, consensus' …
Integrative approaches for finding modular structure in biological networks
A central goal of systems biology is to elucidate the structural and functional architecture of
the cell. To this end, large and complex networks of molecular interactions are being rapidly …
the cell. To this end, large and complex networks of molecular interactions are being rapidly …
Pan-cancer analysis of transcriptional metabolic dysregulation using The Cancer Genome Atlas
Understanding metabolic dysregulation in different disease settings is vital for the safe and
effective incorporation of metabolism-targeted therapeutics in the clinic. Here, using …
effective incorporation of metabolism-targeted therapeutics in the clinic. Here, using …
Systematic evaluation of methods for integration of transcriptomic data into constraint-based models of metabolism
Constraint-based models of metabolism are a widely used framework for predicting flux
distributions in genome-scale biochemical networks. The number of published methods for …
distributions in genome-scale biochemical networks. The number of published methods for …
Unlocking the magic in mycelium: Using synthetic biology to optimize filamentous fungi for biomanufacturing and sustainability
Filamentous fungi drive carbon and nutrient cycling across our global ecosystems, through
its interactions with growing and decaying flora and their constituent microbiomes. The …
its interactions with growing and decaying flora and their constituent microbiomes. The …
[HTML][HTML] Integrating omics data in genome-scale metabolic modeling: a methodological perspective for precision medicine
Recent advancements in omics technologies have generated a wealth of biological data.
Integrating these data within mathematical models is essential to fully leverage their …
Integrating these data within mathematical models is essential to fully leverage their …
Fast reconstruction of compact context-specific metabolic network models
Systemic approaches to the study of a biological cell or tissue rely increasingly on the use of
context-specific metabolic network models. The reconstruction of such a model from high …
context-specific metabolic network models. The reconstruction of such a model from high …