In-vivo Raman spectroscopy: from basics to applications

E Cordero, I Latka, C Matthäus… - Journal of biomedical …, 2018 - spiedigitallibrary.org
For more than two decades, Raman spectroscopy has found widespread use in biological
and medical applications. The instrumentation and the statistical evaluation procedures …

Will data analytics revolution finally bring SERS to the clinic?

AYF Mahmoud, A Teixeira, M Aranda… - TrAC Trends in …, 2023 - Elsevier
Since its discovery, surface-enhanced Raman scattering has shown to be an ultrasensitive
analytical tool. The technique was revolutionized with advances in micro/nanofabrication …

Raman spectroscopy in chronic heart failure diagnosis based on human skin analysis

YA Khristoforova, LA Bratchenko… - Journal of …, 2023 - Wiley Online Library
This work aims at studying Raman spectroscopy in combination with chemometrics as an
alternative fast noninvasive method to detect chronic heart failure (CHF) cases. Optical …

Portable spectroscopic system for in vivo skin neoplasms diagnostics by Raman and autofluorescence analysis

YA Khristoforova, IA Bratchenko… - Journal of …, 2019 - Wiley Online Library
The present paper studies the applicability of a portable cost‐effective spectroscopic system
for the optical screening of skin tumors. in vivo studies of Raman scattering and …

[HTML][HTML] Photoacoustic/ultrasound/optical coherence tomography evaluation of melanoma lesion and healthy skin in a swine model

K Kratkiewicz, R Manwar, A Rajabi-Estarabadi… - Sensors, 2019 - mdpi.com
The marked increase in the incidence of melanoma coupled with the rapid drop in the
survival rate after metastasis has promoted the investigation into improved diagnostic …

Direct observation of the effects of chemical fixation in MNT-1 cells: A SE-ADM and Raman study

R Mastrangelo, T Okada, T Ogura, T Ogura… - Proceedings of the …, 2023 - pnas.org
Aldehydes fixation was accidentally discovered in the early 20th century and soon became a
widely adopted practice in the histological field, due to an excellent staining enhancement in …

Finding reduced Raman spectroscopy fingerprint of skin samples for melanoma diagnosis through machine learning

DC Araújo, AA Veloso, RS de Oliveira Filho… - Artificial Intelligence in …, 2021 - Elsevier
Early-stage detection of cutaneous melanoma can vastly increase the chances of cure.
Excision biopsy followed by histological examination is considered the gold standard for …

[HTML][HTML] Multivariate curve resolution alternating least squares analysis of in vivo skin Raman spectra

I Matveeva, I Bratchenko, Y Khristoforova, L Bratchenko… - Sensors, 2022 - mdpi.com
In recent years, Raman spectroscopy has been used to study biological tissues. However,
the analysis of experimental Raman spectra is still challenging, since the Raman spectra of …

Raman biophysical markers in skin cancer diagnosis

X Feng, AJ Moy, HTM Nguyen, Y Zhang… - Journal of …, 2018 - spiedigitallibrary.org
Raman spectroscopy (RS) has demonstrated great potential for in vivo cancer screening;
however, the biophysical changes that occur for specific diagnoses remain unclear. We …

Raman spectroscopy of human skin for kidney failure detection

LA Bratchenko, IA Bratchenko… - Journal of …, 2021 - Wiley Online Library
The object of this paper is in vivo study of skin spectral‐characteristics in patients with kidney
failure by conventional Raman spectroscopy in near infrared region. The experimental …