Droplet-based digital PCR (ddPCR) and its applications
Y Hou, S Chen, Y Zheng, X Zheng, JM Lin - TrAC Trends in Analytical …, 2023 - Elsevier
As a new generation absolute quantitive PCR technique, droplet-based digital PCR
(ddPCR) provides the benefits of high sensitivity, precision, and reproducibility. A low-cost …
(ddPCR) provides the benefits of high sensitivity, precision, and reproducibility. A low-cost …
Concise whole blood transcriptional signatures for incipient tuberculosis: a systematic review and patient-level pooled meta-analysis
RK Gupta, CT Turner, C Venturini, H Esmail… - The Lancet …, 2020 - thelancet.com
Background Multiple blood transcriptional signatures have been proposed for identification
of active and incipient tuberculosis. We aimed to compare the performance of systematically …
of active and incipient tuberculosis. We aimed to compare the performance of systematically …
Blood transcriptional biomarkers for active pulmonary tuberculosis in a high-burden setting: a prospective, observational, diagnostic accuracy study
CT Turner, RK Gupta, E Tsaliki, JK Roe… - The Lancet …, 2020 - thelancet.com
Background Blood transcriptional signatures are candidates for non-sputum triage or
confirmatory tests of tuberculosis. Prospective head-to-head comparisons of their diagnostic …
confirmatory tests of tuberculosis. Prospective head-to-head comparisons of their diagnostic …
Diagnosis of multisystem inflammatory syndrome in children by a whole-blood transcriptional signature
Background To identify a diagnostic blood transcriptomic signature that distinguishes
multisystem inflammatory syndrome in children (MIS-C) from Kawasaki disease (KD) …
multisystem inflammatory syndrome in children (MIS-C) from Kawasaki disease (KD) …
Blood transcriptomic signatures for symptomatic tuberculosis in an African multicohort study
VM Muwanga, SC Mendelsohn… - European …, 2024 - publications.ersnet.org
Background Multiple host blood transcriptional signatures have been developed as non-
sputum triage tests for tuberculosis (TB). We aimed to compare the diagnostic performance …
sputum triage tests for tuberculosis (TB). We aimed to compare the diagnostic performance …
Transcriptional profiling and deriving a seven-gene signature that discriminates active and latent tuberculosis: an integrative bioinformatics approach
Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis (M. tb.).
Our integrative analysis aims to identify the transcriptional profiling and gene expression …
Our integrative analysis aims to identify the transcriptional profiling and gene expression …
[HTML][HTML] Gene signature discovery and systematic validation across diverse clinical cohorts for TB prognosis and response to treatment
R Vargas, L Abbott, D Bower, N Frahm… - PLOS Computational …, 2023 - journals.plos.org
While blood gene signatures have shown promise in tuberculosis (TB) diagnosis and
treatment monitoring, most signatures derived from a single cohort may be insufficient to …
treatment monitoring, most signatures derived from a single cohort may be insufficient to …
Specific human gene expression in response to infection is an effective marker for diagnosis of latent and active tuberculosis
RNA sequencing and microarray analysis revealed transcriptional markers expressed in
whole blood can differentiate active pulmonary TB (ATB) from other respiratory diseases …
whole blood can differentiate active pulmonary TB (ATB) from other respiratory diseases …
Identification of hub genes for adult patients with sepsis via RNA sequencing
Q Zhang, Y Hu, P Wei, L Shi, L Shi, J Li, Y Zhao… - Scientific Reports, 2022 - nature.com
To screen out potential prognostic hub genes for adult patients with sepsis via RNA
sequencing and construction of a microRNA–mRNA–PPI network and investigate the …
sequencing and construction of a microRNA–mRNA–PPI network and investigate the …
Novel RNA biomarkers improve discrimination of children with tuberculosis disease from those with non-TB pneumonia after in vitro stimulation
The diagnosis of pediatric tuberculosis (TB) poses a challenge for clinical teams worldwide.
TB-mediated changes in the expression of host genes in the peripheral blood can serve as …
TB-mediated changes in the expression of host genes in the peripheral blood can serve as …