The organoid model represents a major breakthrough in cell biology that has revolutionised
biomedical research. Organoids are 3D physiological in vitro structures that recapitulate …

Hepatocellular carcinoma (HCC) is the most common type of liver cancer in adults and has
one of the highest mortality rates of solid cancers. Ninety percent of HCCs are associated …

Understanding the mechanisms underlying evasive resistance in cancer is an unmet
medical need to improve the efficacy of current therapies. In hepatocellular carcinoma …

Simple Summary Hepatocellular carcinoma (HCC) is a highly incident and deadly malignant
neoplasia, and only a few anti-HCC drugs are currently available. Thus, the development of …

Preclinical models of cancer based on the use of human cancer cell lines and mouse
models have enabled discoveries that have been successfully translated into patients. And …

Hepatocellular carcinoma (HCC) represents a global health challenge, and ranks among
one of the most prevalent and deadliest cancers worldwide. Therapeutic advances have …

Hepatocellular carcinoma (HCC) is the most frequent liver cancer, which account for more
than 90% of all liver cancer cases. It is the fifth leading cause of cancer globally and the …

Hepatocellular carcinoma (HCC), the predominant primary liver tumor, remains one of the
most lethal cancers worldwide, despite the advances in therapy in recent years. In addition …

Liver cancer is one of the dominant causes of cancer-related mortality, and the survival rate
of liver cancer is among the lowest for all cancers. Immunotherapy for hepatocellular …

Hepatocellular carcinoma frequently recurs after surgery, necessitating personalized clinical
approaches based on tumor avatar models. However, location-dependent oxygen …