Broad-spectrum antiviral properties of andrographolide

S Gupta, KP Mishra, L Ganju - Archives of virology, 2017 - Springer
Andrographolide, a diterpenoid, is known for its anti-inflammatory effects. It can be isolated
from various plants of the genus Andrographis, commonly known as 'creat'. This purified …

[HTML][HTML] Harnessing reactive oxygen/nitrogen species and inflammation: Nanodrugs for liver injury

M Liu, Q Huang, Y Zhu, L Chen, Y Li, Z Gong, K Ai - Materials Today Bio, 2022 - Elsevier
Overall, 12% of the global population (800 million) suffers from liver disease, which causes 2
million deaths every year. Liver injury involving characteristic reactive oxygen/nitrogen …

Anticancer potential of andrographolide from Andrographis paniculata (Burm. f.) Nees and its mechanisms of action

Z Malik, R Parveen, B Parveen, S Zahiruddin… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance Synthetic drugs used for cancer treatment have side
effects that may be immunosupressive, can cause liver, kidney and cardiac toxicity, and …

Solid lipid nanoparticles for delivery of andrographolide across the blood-brain barrier: in vitro and in vivo evaluation

G Graverini, V Piazzini, E Landucci, D Pantano… - Colloids and Surfaces B …, 2018 - Elsevier
Andrographolide is a major diterpenoid of Andrographis paniculata and possesses several
biological activities, including protection against oxidative stress mediated neurotoxicity …

Antiviral activities of andrographolide and its derivatives: mechanism of action and delivery system

SP Adiguna, JA Panggabean, A Atikana, F Untari… - Pharmaceuticals, 2021 - mdpi.com
Andrographis paniculata (Burm. f.) Nees has been used as a traditional medicine in Asian
countries, especially China, India, Vietnam, Malaysia, and Indonesia. This herbaceous plant …

Phytochemical add-on therapy to DMARDs therapy in rheumatoid arthritis: In vitro and in vivo bases, clinical evidence and future trends

G Kour, SA Haq, BK Bajaj, PN Gupta… - Pharmacological Research, 2021 - Elsevier
The use of biologically active compounds derived from plants ie phytochemicals, have been
known for ages for their pharmacological activities in the treatment of autoimmune disorders …

Chitosan-coated nanoparticles enhanced lung pharmacokinetic profile of voriconazole upon pulmonary delivery in mice

P Paul, S Sengupta, B Mukherjee, TK Shaw… - …, 2018 - Taylor & Francis
Aim: Chitosan-coated polylactic-co-glycolic acid nanoparticles of voriconazole (VChNP)
were developed to increase residence time and provide sustained drug release locally to …

Andrographolide protects liver cells from H2O2 induced cell death by upregulation of Nrf-2/HO-1 mediated via adenosine A2a receptor signalling

SPK Mittal, S Khole, N Jagadish, D Ghosh… - … et Biophysica Acta (BBA …, 2016 - Elsevier
Background Andrographolide, principle constituent of Andrographis paniculata Nees is used
in traditional medicine in Southeast Asia and is known to exhibit various biological activities …

[HTML][HTML] Andrographolide loaded in micro-and nano-formulations: improved bioavailability, target-tissue distribution, and efficacy of the “king of bitters”

M Casamonti, L Risaliti, G Vanti, V Piazzini… - Engineering, 2019 - Elsevier
Andrographolide (AG) is the characteristic constituent of Andrographis paniculata, of the
Acanthaceae family. This plant is a well-known Asian medicinal plant that is widely used in …

The function of miR-145 in colorectal cancer progression; an updated review on related signaling pathways

N Mozammel, M Amini, B Baradaran… - … -Research and Practice, 2023 - Elsevier
MicroRNAs (miRNA) are a broad class of small, highly conserved non-coding RNAs that
largely influence gene expression after transcription through binding to various target …