Per‐and polyfluoroalkyl substance toxicity and human health review: Current state of knowledge and strategies for informing future research

SE Fenton, A Ducatman, A Boobis… - Environmental …, 2021 - Wiley Online Library
Reports of environmental and human health impacts of per‐and polyfluoroalkyl substances
(PFAS) have greatly increased in the peer‐reviewed literature. The goals of the present …

Environmental factors affecting thyroid-stimulating hormone and thyroid hormone levels

M Babić Leko, I Gunjača, N Pleić… - International journal of …, 2021 - mdpi.com
Thyroid hormones are necessary for the normal functioning of physiological systems.
Therefore, knowledge of any factor (whether genetic, environmental or intrinsic) that alters …

Thyroid disrupting effects of old and new generation PFAS

F Coperchini, L Croce, G Ricci, F Magri… - Frontiers in …, 2021 - frontiersin.org
Per-and polyfluoroalkyl substances (PFAS) represent a group of synthetic compounds
widely used in industry plants due to their low grade of degradation, surfactant properties …

Endocrine disruptors in water and their effects on the reproductive system

A Gonsioroski, VE Mourikes, JA Flaws - International journal of molecular …, 2020 - mdpi.com
Anthropogenic contaminants in water can impose risks to reproductive health. Most of these
compounds are known to be endocrine disrupting chemicals (EDCs). EDCs can impact the …

Evaluation of maternal, embryo, and placental effects in CD-1 mice following gestational exposure to perfluorooctanoic acid (PFOA) or hexafluoropropylene oxide …

BE Blake, HA Cope, SM Hall, RD Keys… - Environmental …, 2020 - ehp.niehs.nih.gov
Background: Perfluorooctanoic acid (PFOA) is a poly-and perfluoroalkyl substance (PFAS)
associated with adverse pregnancy outcomes in mice and humans, but little is known …

[HTML][HTML] Evolution of evidence on PFOA and health following the assessments of the C8 Science Panel

K Steenland, T Fletcher, CR Stein, SM Bartell… - Environment …, 2020 - Elsevier
Abstract Background The C8 Science Panel was composed of three epidemiologists
charged with studying the possible health effects of PFOA in a highly exposed population in …

Perfluoroalkyl chemicals and male reproductive health: do PFOA and PFOS increase risk for male infertility?

P Tarapore, B Ouyang - … journal of environmental research and public …, 2021 - mdpi.com
Poly-and perfluoroalkyl substances (PFAS) are manmade synthetic chemicals which have
been in existence for over 70 years. Though they are currently being phased out, their …

Per-and polyfluoroalkyl substances and the associated thyroid cancer risk: A case-control study in China

H Li, M Yang, J Yang, S Seery, C Ma, Y Liu, X Zhang… - Chemosphere, 2023 - Elsevier
The role of perfluoroalkyl and polyfluoroalkyl substances (PFAS) as thyroid carcinogens is
unclear. Therefore, we intended to identify associations between each PFAS congener and …

Improved total organic fluorine methods for more comprehensive measurement of PFAS in industrial wastewater, river water, and air

ALB Forster, Y Zhang, DC Westerman, SD Richardson - Water research, 2023 - Elsevier
Per-and polyfluoroalkyl substances (PFAS) are high-profile environmental contaminants,
many having long persistence in the environment and widespread presence in humans and …

Nuclear receptors are the major targets of endocrine disrupting chemicals

L Toporova, P Balaguer - Molecular and cellular endocrinology, 2020 - Elsevier
Endocrine disrupting chemicals (EDCs) are exogenous substances that are suspected to
cause adverse effects in the endocrine system mainly by acting through their interaction with …