Novel three-component domino reactions of ketones, isatin and amino acids: Synthesis and discovery of antimycobacterial activity of highly functionalised novel …

RS Kumar, SM Rajesh, S Perumal, D Banerjee… - European journal of …, 2010 - Elsevier
One-pot three-component domino reactions of cyclic mono ketones, isatin and sarcosine/
phenylglycine furnishing highly functionalised dispiropyrrolidines in moderate yields are …

A convenient and rapid microwave-assisted synthesis of spirooxindoles in aqueous medium and their antimicrobial activities

PR Mali, LC Rao, VM Bangade, PK Shirsat… - New Journal of …, 2016 - pubs.rsc.org
A simple, ecofriendly and one-pot three-component aqueous phase protocol is developed
for the synthesis of functionalized spirooxindole derivatives by the reaction of isatin, β …

[HTML][HTML] Additive-assisted regioselective 1, 3-dipolar cycloaddition of azomethine ylides with benzylideneacetone

C Peng, J Ren, JA **ao, H Zhang… - Beilstein Journal of …, 2014 - beilstein-journals.org
Dipolar cycloadditions of isatins, benzylamine and benzylideneacetones were studied to
prepare a series of novel spiropyrrolidine-oxindoles–4′-acetyl-3′, 5′-diarylspiro …

Synthesis, structural determination, in vitro antioxidant and antibacterial efficacy of dispirooxindolopyrrolidine embedded indole heterocycle

N Arumugam, AI Almansour, MF Alkaltham… - Journal of Molecular …, 2024 - Elsevier
Synthesis of dispirooxindolopyrrolidine embedded indole hybrid heterocycle was achieved
in excellent yield employing intermolecular 1, 3-dipolar cycloaddition cascade reaction …

Synthesis and crystal structures of 5'-phenylspiro [indoline-3, 2'-pyrrolidin]-2-one derivatives

JK Sundar, SM Rajesh, J Sivamani, S Perumal… - Chemistry Central …, 2011 - Springer
Background The spiro-indole-pyrrolidine ring system is a frequently encountered structural
motif in many biologically important and pharmacologically relevant alkaloids. The …