Microbial-derived metabolites as a risk factor of age-related cognitive decline and dementia
A consequence of our progressively ageing global population is the increasing prevalence
of worldwide age-related cognitive decline and dementia. In the absence of effective …
of worldwide age-related cognitive decline and dementia. In the absence of effective …
Social isolation and cognitive function in later life: a systematic review and meta-analysis
IEM Evans, A Martyr, R Collins… - Journal of Alzheimer's …, 2019 - content.iospress.com
Background: There is some evidence to suggest that social isolation may be associated with
poor cognitive function in later life. However, findings are inconsistent and there is wide …
poor cognitive function in later life. However, findings are inconsistent and there is wide …
Brain age prediction using deep learning uncovers associated sequence variants
Abstract Machine learning algorithms can be trained to estimate age from brain structural
MRI. The difference between an individual's predicted and chronological age, predicted age …
MRI. The difference between an individual's predicted and chronological age, predicted age …
[HTML][HTML] Multimodality neuroimaging brain-age in UK biobank: relationship to biomedical, lifestyle, and cognitive factors
JH Cole - Neurobiology of aging, 2020 - Elsevier
The brain-age paradigm is proving increasingly useful for exploring aging-related disease
and can predict important future health outcomes. Most brain-age research uses structural …
and can predict important future health outcomes. Most brain-age research uses structural …
[HTML][HTML] PET imaging of tau deposition in the aging human brain
Tau pathology is a hallmark of Alzheimer's disease (AD) but also occurs in normal cognitive
aging. Using the tau PET agent 18 F-AV-1451, we examined retention patterns in cognitively …
aging. Using the tau PET agent 18 F-AV-1451, we examined retention patterns in cognitively …
Brain age and other bodily 'ages': implications for neuropsychiatry
As our brains age, we tend to experience cognitive decline and are at greater risk of
neurodegenerative disease and dementia. Symptoms of chronic neuropsychiatric diseases …
neurodegenerative disease and dementia. Symptoms of chronic neuropsychiatric diseases …
Association of late-life depression with cognitive impairment: evidence from a cross-sectional study among older adults in India
Background Late-life depression (LLD) is considered as a prodrome to dementia and plays
a major role in the development of long-term cognitive disabilities. We aimed to estimate the …
a major role in the development of long-term cognitive disabilities. We aimed to estimate the …
[HTML][HTML] Computerized cognitive training in cognitively healthy older adults: a systematic review and meta-analysis of effect modifiers
Computerized Cognitive Training in Cognitively Healthy Older Adults: A Systematic Review and
Meta-Analysis of Effect Modifiers | PLOS Medicine Skip to main content Advertisement PLOS …
Meta-Analysis of Effect Modifiers | PLOS Medicine Skip to main content Advertisement PLOS …
Obesity and related consequences to ageing
M Jura, LP Kozak - Age, 2016 - Springer
Obesity has become a major public health problem. Given the current increase in life
expectancy, the prevalence of obesity also raises steadily among older age groups. The …
expectancy, the prevalence of obesity also raises steadily among older age groups. The …
Cognitive function trajectories and their determinants in older people: 8 years of follow-up in the English Longitudinal Study of Ageing
P Zaninotto, GD Batty, M Allerhand… - J Epidemiol Community …, 2018 - jech.bmj.com
Background Maintaining cognitive function is an important aspect of healthy ageing. In this
study, we examined age trajectories of cognitive decline in a large nationally representative …
study, we examined age trajectories of cognitive decline in a large nationally representative …