[HTML][HTML] Umbelliferone and its synthetic derivatives as suitable molecules for the development of agents with biological activities: a review of their pharmacological and …

A Kornicka, Ł Balewski, M Lahutta, J Kokoszka - Pharmaceuticals, 2023 - mdpi.com
Umbelliferone (UMB), known as 7-hydroxycoumarin, hydrangine, or skimmetine, is a
naturally occurring coumarin in the plant kingdom, mainly from the Umbelliferae family that …

Anti-Cholinesterase and Anti-α-Amylase Activities and Neuroprotective Effects of Carvacrol and p-Cymene and Their Effects on Hydrogen Peroxide Induced Stress in …

L Caputo, G Amato, L De Martino, V De Feo… - International Journal of …, 2023 - mdpi.com
Several researchers have demonstrated the health and pharmacological properties of
carvacrol and p-cymene, monoterpenes of aromatic plants. This study investigated these …

Use of Tox21 screening data to evaluate the covid-19 drug candidates for their potential toxic effects and related pathways

S Sakamuru, R Huang, M **a - Frontiers in Pharmacology, 2022 - frontiersin.org
Currently, various potential therapeutic agents for coronavirus disease-2019 (COVID-19), a
global pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS …

Enterobacter hormaechei-Driven Novel Biosynthesis of Tin Oxide Nanoparticles and Evaluation of Their Anti-aging, Cytotoxic, and Enzyme Inhibition Potential

M Rizwan, S Faisal, MH Tariq, S Zafar, A Khan… - ACS …, 2023 - ACS Publications
Nanotechnology is a research hotspot that has gained considerable interest due to its
potential inferences in the bioscience, medical, and engineering disciplines. The present …

Anti-Cholinergic Effects of the Phenolic Extract from the Astragalus crenatus Plant: A Computational and Network Pharmacology Study

S Lekmine, O Benslama, H Tahraoui, MS Ola… - Pharmaceuticals, 2024 - mdpi.com
Investigations into cholinesterase inhibition have received attention from researchers in
recent years for the treatment of Alzheimer's disease. Cholinesterase enzymes, namely …

Synthesis of 4-substituted benzyl-2-triazole-linked-tryptamine-paeonol derivatives and evaluation of their selective inhibitions against butyrylcholinesterase and …

JM Oh, Y Kang, JH Hwang, JH Park, WH Shin… - International Journal of …, 2022 - Elsevier
Cholinesterase (ChE) and monoamine oxidase (MAO) inhibitors are being used and
developed to treat Alzheimer's disease (AD), a major type of dementia patients. Fifteen 4 …

Some bioactivities of isolated apigenin-7-O-glucoside and luteolin-7-O-glucoside

E Sezen Karaoğlan, H Hancı, M Koca, C Kazaz - Applied Sciences, 2023 - mdpi.com
In this study, we aimed to isolate compounds from Stachys lavandulifolia (Lamiaceae) by
chromatographic methods and perform tyrosinase, acetylcholinesterase …

[HTML][HTML] Ultrasound-Assisted Extraction, LC–MS/MS Analysis, Anticholinesterase, and Antioxidant Activities of Valuable Natural Metabolites from Astragalus armatus …

S Lekmine, S Bendjedid, O Benslama, AI Martín-García… - Antioxidants, 2022 - mdpi.com
The Astragalus armatus Willd. plant's phenolic constituent extraction and identification were
optimized using the ultrasound-assisted extraction (UAE) method and the LC–MS/MS …

Chemical Composition, Biological Activities and In Silico Analysis of Essential Oils of Three Endemic Prangos Species from Turkey

G Zengin, MF Mahomoodally, E Yıldıztugay, S Jugreet… - Molecules, 2022 - mdpi.com
In this study, the essential oils (EOs) obtained from three endemic Prangos species from
Turkey (P. heyniae, P. meliocarpoides var. meliocarpoides, and P. uechtritzii) were studied …

Synthesis, biological evaluation, molecular docking, and MD simulation of novel 2, 4-disubstituted quinazoline derivatives as selective butyrylcholinesterase inhibitors …

S Sadeghian, R Razmi, S Khabnadideh… - Scientific Reports, 2024 - nature.com
Alzheimer's disease is the most prevalent neurodegenerative disorder characterized by
significant memory loss and cognitive impairments. Studies have shown that the expression …