Drug repurposing is promoted as a cost-and time-effective mechanism for providing new
medicines. Often, however, there is insufficient consideration by academic researchers of …

Human malignancies are one of the major health-related issues though out the world and
anticipated to rise in the future. The development of novel drugs/agents requires a huge …

Prostate cancer (PC) is the most common cancer in men and the second leading cause of
cancer-related death worldwide. Many therapeutic advances over the last two decades have …

Invasive fungal infections remain a major cause of morbidity and mortality in
immunocompromised patients, and such infections are a substantial burden to healthcare …

Overcoming multidrug resistance represents a major challenge for cancer treatment. In the
search for new chemotherapeutics to treat malignant diseases, drug repurposing gained a …

Diclofenac (DCF) is a well-known and widely used non-steroidal anti-inflammatory drug
(NSAID), with a range of actions which are of interest in an oncological context. While there …

Background The dismal prognosis of glioblastoma (GBM) may be related to the ability of
GBM cells to develop mechanisms of treatment resistance. We designed a protocol called …

Itraconazole is as an antifungal medication used to treat systemic fungal infections.
Recently, it has been reported to be effective in suppressing tumor growth by inhibiting the …

Drug repositioning has gained attention from both academia and pharmaceutical companies
as an auxiliary process to conventional drug discovery. Chemotherapeutic agents have …

Itraconazole, a common anti-fungal agent, has demonstrated potential anticancer activity,
including reversing chemoresistance mediated by P-glycoprotein, modulating the signal …