The role of immune cells and mediators in preeclampsia

E Deer, O Herrock, N Campbell, D Cornelius… - Nature Reviews …, 2023‏ - nature.com
Preeclampsia is a hypertensive disorder of major concern in pregnancy than can lead to
intrauterine growth restriction, placental abruption and stillbirth. The pathophysiology of …

Anti-CD20 therapies in multiple sclerosis: From pathology to the clinic

J de Sèze, E Maillart, A Gueguen, DA Laplaud… - Frontiers in …, 2023‏ - frontiersin.org
The immune system plays a significant role in multiple sclerosis. While MS was historically
thought to be T cell-mediated, multiple pieces of evidence now support the view that B cells …

Family planning considerations in people with multiple sclerosis

KM Krysko, R Dobson, R Alroughani… - The Lancet …, 2023‏ - thelancet.com
Multiple sclerosis is often diagnosed in patients who are planning on having children.
Although multiple sclerosis does not negatively influence most pregnancy outcomes, less is …

Diagnosis and treatment of NMO spectrum disorder and MOG-encephalomyelitis

N Borisow, M Mori, S Kuwabara, M Scheel… - Frontiers in …, 2018‏ - frontiersin.org
Neuromyelitis optica spectrum disorders (NMOSD) are autoantibody mediated chronic
inflammatory diseases. Serum antibodies (Abs) against the aquaporin-4 water channel lead …

Treatment of women with multiple sclerosis planning pregnancy

KM Krysko, R Bove, R Dobson, V Jokubaitis… - … Treatment Options in …, 2021‏ - Springer
Abstract Purpose of Review We review data available for treatment of multiple sclerosis (MS)
before, during, and after pregnancy. We present recent data on disease-modifying therapies …

[HTML][HTML] Monoclonal antibodies in the treatment of relapsing multiple sclerosis: an overview with emphasis on pregnancy, vaccination, and risk management

N Krajnc, G Bsteh, T Berger, J Mares, HP Hartung - Neurotherapeutics, 2022‏ - Elsevier
Monoclonal antibodies have become a mainstay in the treatment of patients with relapsing
multiple sclerosis (RMS) and provide some benefit to patients with primary progressive MS …

Natalizumab, fingolimod, and dimethyl fumarate use and pregnancy-related relapse and disability in women with multiple sclerosis

WZ Yeh, PA Widyastuti, A Van der Walt, J Stankovich… - Neurology, 2021‏ - neurology.org
Objective To investigate pregnancy-related disease activity in a contemporary multiple
sclerosis (MS) cohort. Methods Using data from the MSBase Registry, we included …

Sex effects across the lifespan in women with multiple sclerosis

KM Krysko, JS Graves, R Dobson… - Therapeutic …, 2020‏ - journals.sagepub.com
Multiple sclerosis (MS) is an autoimmune inflammatory demyelinating central nervous
system disorder that is more common in women, with onset often during reproductive years …

Sex differences in autoimmune disorders of the central nervous system

SM Gold, A Willing, F Leypoldt, F Paul… - Seminars in …, 2019‏ - Springer
Stronger adaptive immune responses in females can be observed in different mammals,
resulting in better control of infections compared to males. However, this presumably …

[HTML][HTML] Update on treatment in multiple sclerosis

I Callegari, T Derfuss, E Galli - La Presse Médicale, 2021‏ - Elsevier
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system. In
recent years, many disease-modifying therapies (DMT) have been approved for MS …