The past decade has witnessed remarkable advances in the simultaneous measurement of
neuronal activity across many brain regions, enabling fundamentally new explorations of the …

Recent advances combining two-photon calcium imaging and two-photon optogenetics with
computer-generated holography now allow us to read and write the activity of large …

Understanding how cortical circuits generate complex behavior requires investigating the
cell types that comprise them. Functional differences across pyramidal neuron (PyN) types …

Simple Summary We review advances in the properties of calcium sensors, microscopy, and
data analysis that have brought about the ability to image large contiguous regions of the …

Cortical responses to visual stimuli are believed to rely on the geniculo-striate pathway.
However, recent work has challenged this notion by showing that responses in the …

Many of the sensations experienced by an organism are caused by their own actions, and
accurately anticipating both the sensory features and timing of self-generated stimuli is …

Neurophotonics was launched in 2014 coinciding with the launch of the BRAIN Initiative
focused on development of technologies for advancement of neuroscience. For the last …

Understanding the basis of brain function requires knowledge of cortical operations over
wide spatial scales and the quantitative analysis of brain activity in well-defined brain …

A central goal of neuroscience is to understand how the brain transforms external stimuli
and internal bodily signals into patterns of activity that underlie cognition, emotional states …

Functional connectivity (FC) can provide insight into cortical circuit dysfunction in
neuropsychiatric disorders. However, dynamic changes in FC related to locomotion with …